Effects of carbamazepine on plasma haloperidol levels

M. W. Jann, L. Ereshefsky, Stephen R Saklad, D. R. Seidel, C. M. Davis, N. R. Burch, C. L. Bowden

Research output: Contribution to journalArticle

90 Citations (Scopus)

Abstract

Plasma haloperidol levels were monitored in three schizophrenic patients when carbamazepine was either added or discontinued. The percent decrease in plasma haloperidol levels due to concomitant carbamazepine therapy was between 59% and 61%. The effects of carbamazepine on plasma haloperidol levels were noted to occur in 2 to 3 weeks. Although no adverse effects occurred in the patients during therapy, careful monitoring of clinical symptoms and plasma haloperidol levels is recommended.

Original languageEnglish (US)
Pages (from-to)106-109
Number of pages4
JournalJournal of Clinical Psychopharmacology
Volume5
Issue number2
StatePublished - 1985

Fingerprint

Carbamazepine
Haloperidol
Therapeutics

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Pharmacology (medical)
  • Pharmacology, Toxicology and Pharmaceutics(all)

Cite this

Jann, M. W., Ereshefsky, L., Saklad, S. R., Seidel, D. R., Davis, C. M., Burch, N. R., & Bowden, C. L. (1985). Effects of carbamazepine on plasma haloperidol levels. Journal of Clinical Psychopharmacology, 5(2), 106-109.

Effects of carbamazepine on plasma haloperidol levels. / Jann, M. W.; Ereshefsky, L.; Saklad, Stephen R; Seidel, D. R.; Davis, C. M.; Burch, N. R.; Bowden, C. L.

In: Journal of Clinical Psychopharmacology, Vol. 5, No. 2, 1985, p. 106-109.

Research output: Contribution to journalArticle

Jann, MW, Ereshefsky, L, Saklad, SR, Seidel, DR, Davis, CM, Burch, NR & Bowden, CL 1985, 'Effects of carbamazepine on plasma haloperidol levels', Journal of Clinical Psychopharmacology, vol. 5, no. 2, pp. 106-109.
Jann MW, Ereshefsky L, Saklad SR, Seidel DR, Davis CM, Burch NR et al. Effects of carbamazepine on plasma haloperidol levels. Journal of Clinical Psychopharmacology. 1985;5(2):106-109.
Jann, M. W. ; Ereshefsky, L. ; Saklad, Stephen R ; Seidel, D. R. ; Davis, C. M. ; Burch, N. R. ; Bowden, C. L. / Effects of carbamazepine on plasma haloperidol levels. In: Journal of Clinical Psychopharmacology. 1985 ; Vol. 5, No. 2. pp. 106-109.
@article{6ce72ff2c3b04d5896998fc64715282e,
title = "Effects of carbamazepine on plasma haloperidol levels",
abstract = "Plasma haloperidol levels were monitored in three schizophrenic patients when carbamazepine was either added or discontinued. The percent decrease in plasma haloperidol levels due to concomitant carbamazepine therapy was between 59{\%} and 61{\%}. The effects of carbamazepine on plasma haloperidol levels were noted to occur in 2 to 3 weeks. Although no adverse effects occurred in the patients during therapy, careful monitoring of clinical symptoms and plasma haloperidol levels is recommended.",
author = "Jann, {M. W.} and L. Ereshefsky and Saklad, {Stephen R} and Seidel, {D. R.} and Davis, {C. M.} and Burch, {N. R.} and Bowden, {C. L.}",
year = "1985",
language = "English (US)",
volume = "5",
pages = "106--109",
journal = "Journal of Clinical Psychopharmacology",
issn = "0271-0749",
publisher = "Lippincott Williams and Wilkins",
number = "2",

}

TY - JOUR

T1 - Effects of carbamazepine on plasma haloperidol levels

AU - Jann, M. W.

AU - Ereshefsky, L.

AU - Saklad, Stephen R

AU - Seidel, D. R.

AU - Davis, C. M.

AU - Burch, N. R.

AU - Bowden, C. L.

PY - 1985

Y1 - 1985

N2 - Plasma haloperidol levels were monitored in three schizophrenic patients when carbamazepine was either added or discontinued. The percent decrease in plasma haloperidol levels due to concomitant carbamazepine therapy was between 59% and 61%. The effects of carbamazepine on plasma haloperidol levels were noted to occur in 2 to 3 weeks. Although no adverse effects occurred in the patients during therapy, careful monitoring of clinical symptoms and plasma haloperidol levels is recommended.

AB - Plasma haloperidol levels were monitored in three schizophrenic patients when carbamazepine was either added or discontinued. The percent decrease in plasma haloperidol levels due to concomitant carbamazepine therapy was between 59% and 61%. The effects of carbamazepine on plasma haloperidol levels were noted to occur in 2 to 3 weeks. Although no adverse effects occurred in the patients during therapy, careful monitoring of clinical symptoms and plasma haloperidol levels is recommended.

UR - http://www.scopus.com/inward/record.url?scp=0021950571&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0021950571&partnerID=8YFLogxK

M3 - Article

VL - 5

SP - 106

EP - 109

JO - Journal of Clinical Psychopharmacology

JF - Journal of Clinical Psychopharmacology

SN - 0271-0749

IS - 2

ER -