Effects of a bovine pineal peptidic fraction (E5) on plasma and pituitary levels of LH, FSH and prolactin

Mary K. Vaughan, B. A. Richardson, L. Y. Johnson, R. J. Reiter, P. Pevet, C. Neascu

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2 Scopus citations


Pituitary levels of prolactin were significantly diminished after 5 s.c. injections spaced 12 h apart of 5 μg of a partially purified bovine pineal peptide fraction (E5) in both intact and castrated rats. E5 treatment did not significantly affect the castration-induced changes in plasma luteinizing hormone (LH), follicle-stimulating hormone (FSH) or pituitary LH but did partially block the pituitary fall in FSH in castrated animals.

Original languageEnglish (US)
Pages (from-to)871-872
Number of pages2
Issue number7
Publication statusPublished - Jul 1982


ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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