Effectiveness of silver diamine fluoride in arresting dental caries in residents living in nursing homes: A randomized controlled trial

Objective: The primary objective of this randomized controlled trial was to determine the effectiveness of a single application of 38% silver diamine fluoride (SDF) solution in arresting and controlling active accessible caries compared to no treatment among adults aged 18 years and older residing in nursing homes or long-term care facilities. Many patients cannot receive standard-of-care dental treatment due to their medical conditions and inability to undergo anesthesia. All teeth in the control group will be treated with SDF at the conclusion of the study. Methods: This study enrolled 39 adults aged 18 or older with 188 active lesions from nine San Antonio, Texas, nursing home facilities. Teeth were randomized and divided into two treatment and control groups. Each treatment tooth was paired with a control in the same oral cavity. Accessible carious lesions were treated with a single application of 38% SDF solution. Teeth were re-evaluated at 3 weeks where control groups also received SDF treatment. Results: The treatment group demonstrated caries arrest in 77 (81.9%) teeth compared to 0 in the control group (0%). Notably, within the treatment group 14 of the 17 teeth with no caries arrest were posterior teeth (82.4%). Conclusions: Our results suggest that a single application of 38% SDF solution is an effective measure for arresting and controlling caries compared to standard oral hygiene maintenance. Our research team recommends the regular use of a single application of SDF solution in marginalized populations given the possible public health, oral health, social, and economic benefits.