Effect of zinc administration on the growth of L1210 and Bw5147 tumors in mice

Jerry L. Phillips; Peter J. Sheridan

doi:10.1093/jnci/57.2.361

Effect of zinc administration on the growth of L1210 and Bw5147 tumors in mice

Jerry L. Phillips, Peter J. Sheridan

Department of Cell Systems & Anatomy

Research output: Contribution to journal › Article › peer-review

23 Scopus citations

Abstract

Aqueous zinc acetate injected ip prevented tumor growth in 50–70% of BDF male mice previously inoculated ip with L1210 leukemia cells. However, aqueous zinc acetate injected sc did not prevent tumor growth in AKR/J mice inoculated im with BW5147 lymphatic leukemia cetrs. In the latter mice, only a small but statistically significant increase in mean survival was noted.

Original language	English (US)
Pages (from-to)	361-363
Number of pages	3
Journal	Journal of the National Cancer Institute
Volume	57
Issue number	2
DOIs	https://doi.org/10.1093/jnci/57.2.361
State	Published - 1976

ASJC Scopus subject areas

Oncology
Cancer Research

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10.1093/jnci/57.2.361

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title = "Effect of zinc administration on the growth of L1210 and Bw5147 tumors in mice",

abstract = "Aqueous zinc acetate injected ip prevented tumor growth in 50–70% of BDF male mice previously inoculated ip with L1210 leukemia cells. However, aqueous zinc acetate injected sc did not prevent tumor growth in AKR/J mice inoculated im with BW5147 lymphatic leukemia cetrs. In the latter mice, only a small but statistically significant increase in mean survival was noted.",

author = "Phillips, {Jerry L.} and Sheridan, {Peter J.}",

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AU - Phillips, Jerry L.

AU - Sheridan, Peter J.

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N2 - Aqueous zinc acetate injected ip prevented tumor growth in 50–70% of BDF male mice previously inoculated ip with L1210 leukemia cells. However, aqueous zinc acetate injected sc did not prevent tumor growth in AKR/J mice inoculated im with BW5147 lymphatic leukemia cetrs. In the latter mice, only a small but statistically significant increase in mean survival was noted.

AB - Aqueous zinc acetate injected ip prevented tumor growth in 50–70% of BDF male mice previously inoculated ip with L1210 leukemia cells. However, aqueous zinc acetate injected sc did not prevent tumor growth in AKR/J mice inoculated im with BW5147 lymphatic leukemia cetrs. In the latter mice, only a small but statistically significant increase in mean survival was noted.

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Effect of zinc administration on the growth of L1210 and Bw5147 tumors in mice

Abstract

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