Effect of triple dye on staphylococcal colonization in the newborn infant

Rosita S. Pildes, Rajam S. Ramamurthy, D. Vidyasagar

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34 Scopus citations


The effectiveness of triple dye, hexachlorophene, or liquid soap bathing in the reduction of staphylococcal colonization rate was evaluated in a study of 1,117 infants. Cord colonization rate was 10.5 per cent in the triple dye group, 41.1 per cent in the hexachlorophene group, and 71.5 per cent in the control group. These differences are significant (p<0.001). Nasal colonization rate was similar in the triple dye (12.4 per cent) and hexachlorophene groups (15.8 per cent), and both were significantly (p<0.001) lower than the rate in the control group (48.3 per cent). After the study was terminated, triple dye was applied to the cords of all infants admitted to the nursery. In 1,147 infants cultured during the following six months, the staphylococcal cord colonization rate was 1.8 per cent and the nasal colonization was 5.2 per cent. Triple dye was considered an effective agent in maintaining low staphylococcal colonization rates in newborn nurseries.

Original languageEnglish (US)
Pages (from-to)987-990
Number of pages4
JournalThe Journal of pediatrics
Issue number6
StatePublished - Jun 1973

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health


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