Effect of synthetic luteinizing hormone releasing hormone on prolactin secretion from clonal pituitary cells

Damon C. Herbert, Edward G. Rennels

Research output: Contribution to journalArticlepeer-review

22 Scopus citations

Abstract

The influence of LHRH, an analog of LHRH (hydroxy-PRO1) and inulin on prolactin (PRL) secretion was studied using a clonal strain of pituitary cells. At low concentrations, 0.08 ng to 8 ng/ml, LHRH stimulated PRL release while at higher concentrations the opposite effect was obtained. The analog of LHRH inhibited PRL secretion at all concentrations studied. No effect was measured with inulin.

Original languageEnglish (US)
Pages (from-to)133-138
Number of pages6
JournalBiochemical and Biophysical Research Communications
Volume79
Issue number1
DOIs
StatePublished - Nov 7 1977

ASJC Scopus subject areas

  • Biophysics
  • Biochemistry
  • Molecular Biology
  • Cell Biology

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