TY - JOUR
T1 - Effect of superior cervical ganglionectomy on the ultrastructure of the pinealocyte in the cotton rat (Sigmodon hispidus)
AU - Karasek, Michal
AU - Petterborg, Larry J.
AU - King, Thomas S.
AU - Hansen, John T.
AU - Reiter, Russel J.
N1 - Funding Information:
The authors wish to thank Ms. Gwynne Duke for her excellent technical assistance and Ms. Nora Dimas for typing the manuscript. This study was supported by NSF Grant PCM 8003441 to R.J.R. and by a grant from the Polish Academy of Sciences, within project 10.4, to M.K. T.S.K. was a postdoctoral fellow in the Center for Training in Reproductive Biology HD 07139. J.T.H. is the recipient of NIH RCDA K04 HL-00680.
PY - 1983/7
Y1 - 1983/7
N2 - The ultrastructure of pinealocytes was examined morphometrically in superior cervical ganglionectomized and sham-operated cotton rats. Following denervation, the pinealocytes decreased in size. Reduced areas of the nucleoli, Golgi apparatus, granular endoplasmic reticulum, mitochondria, and vacuoles containing a flocculent material as well as a decreased number of dense-core vesicles were noted. In contrast, the numbers of "synaptic" ribbons and ribbon fields increased. The nature of ultrastructural changes observed in the cotton rat pinealocyte after sympathectomy may indicate a diminution of the presumptive secretory processes of this cell. The presence of a small number of myelinated and unmyelinated axons in the pineal gland of the cotton rat following superior cervical ganglionectomy suggests that the sympathetic nerve fibers from the superior cervical ganglia do not comprise the only source of innervation to the pineal. Additionally, the presence of striated muscle fibers has been observed in the present study in the pineal gland of the cotton rat which heretofore has not been reported in this species.
AB - The ultrastructure of pinealocytes was examined morphometrically in superior cervical ganglionectomized and sham-operated cotton rats. Following denervation, the pinealocytes decreased in size. Reduced areas of the nucleoli, Golgi apparatus, granular endoplasmic reticulum, mitochondria, and vacuoles containing a flocculent material as well as a decreased number of dense-core vesicles were noted. In contrast, the numbers of "synaptic" ribbons and ribbon fields increased. The nature of ultrastructural changes observed in the cotton rat pinealocyte after sympathectomy may indicate a diminution of the presumptive secretory processes of this cell. The presence of a small number of myelinated and unmyelinated axons in the pineal gland of the cotton rat following superior cervical ganglionectomy suggests that the sympathetic nerve fibers from the superior cervical ganglia do not comprise the only source of innervation to the pineal. Additionally, the presence of striated muscle fibers has been observed in the present study in the pineal gland of the cotton rat which heretofore has not been reported in this species.
UR - http://www.scopus.com/inward/record.url?scp=0020787768&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0020787768&partnerID=8YFLogxK
U2 - 10.1016/0016-6480(83)90105-3
DO - 10.1016/0016-6480(83)90105-3
M3 - Article
C2 - 6350108
AN - SCOPUS:0020787768
VL - 51
SP - 131
EP - 137
JO - General and Comparative Endocrinology
JF - General and Comparative Endocrinology
SN - 0016-6480
IS - 1
ER -