Effect of repeated administration of novel stressors on central beta adrenoceptors

M. P. Areso; A. Frazer

doi:10.1007/BF01250709

Effect of repeated administration of novel stressors on central beta adrenoceptors

M. P. Areso, A. Frazer

Research output: Contribution to journal › Article › peer-review

17 Scopus citations

Abstract

Subtypes of beta adrenoceptors were measured in 17 different areas of brain in rats exposed for 12 days to novel Stressors. Mild stress such as individual housing and handling caused no change in beta₁ and beta₂ adrenoceptors in comparison with that measured in rats that were group housed and never handled. Exposure of rats to more severe Stressors did reduce significantly the binding of¹²⁵I-iodopindolol (¹²⁵I-IPIN) to beta₁ adrenoceptors, but not beta₂ adrenoceptors, only in the lateral and basolateral nuclei of the amygdala.

Original language	English (US)
Pages (from-to)	229-235
Number of pages	7
Journal	Journal of Neural Transmission
Volume	86
Issue number	3
DOIs	https://doi.org/10.1007/BF01250709
State	Published - Oct 1991
Externally published	Yes

Keywords

Stress
amygdala
beta adrenoceptors

ASJC Scopus subject areas

Neurology
Clinical Neurology
Psychiatry and Mental health
Biological Psychiatry

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10.1007/BF01250709

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abstract = "Subtypes of beta adrenoceptors were measured in 17 different areas of brain in rats exposed for 12 days to novel Stressors. Mild stress such as individual housing and handling caused no change in beta1 and beta2 adrenoceptors in comparison with that measured in rats that were group housed and never handled. Exposure of rats to more severe Stressors did reduce significantly the binding of125I-iodopindolol (125I-IPIN) to beta1 adrenoceptors, but not beta2 adrenoceptors, only in the lateral and basolateral nuclei of the amygdala.",

keywords = "Stress, amygdala, beta adrenoceptors",

author = "Areso, {M. P.} and A. Frazer",

year = "1991",

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AU - Frazer, A.

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AB - Subtypes of beta adrenoceptors were measured in 17 different areas of brain in rats exposed for 12 days to novel Stressors. Mild stress such as individual housing and handling caused no change in beta1 and beta2 adrenoceptors in comparison with that measured in rats that were group housed and never handled. Exposure of rats to more severe Stressors did reduce significantly the binding of125I-iodopindolol (125I-IPIN) to beta1 adrenoceptors, but not beta2 adrenoceptors, only in the lateral and basolateral nuclei of the amygdala.

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KW - amygdala

KW - beta adrenoceptors

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ER -

Effect of repeated administration of novel stressors on central beta adrenoceptors

Abstract

Keywords

ASJC Scopus subject areas

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