Effect of photoperiod and pineal indoles on the reproductive system of young female white-footed mice

L. J. Petterborg, Russel J Reiter

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Exposure of prepubertal female mice to short photoperiod (LD 8:16) for 3 weeks resulted in a significant inhibition of reproductive tract growth compared with mice maintained in long photoperiod (LD 16:8). Chronic subcutaneous melatonin-beeswax implants containing 1 mg melatonin also produced an inhibition of the reproductive system of these animals. The repressive effects of melatonin appear not to be influenced by photoperiod since comparable results were obtained from groups of mice bearing implants in long and short photoperiods. In addition, the ability of beeswax implants containing various indolic compounds (melatonin, serotonin, 5-methoxytryptamine, 5-methoxyindole-3-acetic acid, and N-acetylserotonin) to inhibit the growth of the reproductive system of this species were compared. Only implants containing melatonin or serotonin caused any significant repression of uterine and ovarian weights.

Original languageEnglish (US)
Pages (from-to)149-155
Number of pages7
JournalJournal of Neural Transmission
Volume55
Issue number2
DOIs
StatePublished - Jun 1982

Fingerprint

Peromyscus
Indoles
Photoperiod
Melatonin
Serotonin
5-Methoxytryptamine
Growth
Weights and Measures

Keywords

  • melatonin
  • ovary
  • Photoperiod
  • pineal indoles
  • uterus
  • white-footed mouse

ASJC Scopus subject areas

  • Neuroscience(all)
  • Medicine(all)

Cite this

Effect of photoperiod and pineal indoles on the reproductive system of young female white-footed mice. / Petterborg, L. J.; Reiter, Russel J.

In: Journal of Neural Transmission, Vol. 55, No. 2, 06.1982, p. 149-155.

Research output: Contribution to journalArticle

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