Effect of patient comorbidities on filling of antihypertensive prescriptions

Tara Lagu, Mark G. Weiner, Susan Eachus, Simon S K Tang, J. Sanford Schwartz, Barbara J. Turner

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Objectives: To evaluate the extent of patient failure to fill antihypertensive prescriptions and to test the hypothesis that the presence of non-cardiovascular disease is negatively associated with filling an antihypertensive prescription, and, conversely, that the presence of cardiovascular disease is positively associated with filling an antihypertensive prescription. Study Design: Cross-sectional. Methods: We sampled prescriptions written for 327 African Americans aged ≥18 years. Patients were enrolled in a Medicaid managed care plan and treated in 6 primary care practices between January 1, 2003, and February 8, 2005. Prescription filling was defined as a match between a new or renewed electronic prescription and an insurance claim within the next 30 days. We assessed the association of comorbidity type with filling an antihypertensive prescription by using an adjusted logistic regression model that accounted for clustering of prescriptions within patients. Results: Of 1742 antihypertensive prescriptions, 1309 (75.1%) were filled. Prescriptions written for persons with 5 or more noncardiovascular comorbidities were significantly more likely to be filled (adjusted odds ratio [OR], 1.59; 95% confidence interval [CI], 1.07 ± 2.36) versus those for persons with fewer noncardiovascular comorbidities. The presence of cardiovascular comorbidities was not associated with filling of an antihypertensive prescription (adjusted OR, 0.72; 95% CI, 0.45-1.14). Conclusion: Many antihypertensive prescriptions were not filled. Different types of patient comorbidity may differentially impact prescription filling. Further studies should examine whether these results generalize to other populations.

Original languageEnglish (US)
Pages (from-to)24-30
Number of pages7
JournalAmerican Journal of Managed Care
Volume15
Issue number1
StatePublished - Jan 2009
Externally publishedYes

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Antihypertensive Agents
Prescriptions
Comorbidity
Pharmaceutical Services Insurance
Logistic Models
Electronic Prescribing
Odds Ratio
Confidence Intervals
Medicaid
Managed Care Programs
African Americans
Cluster Analysis
Primary Health Care
Cardiovascular Diseases
Cross-Sectional Studies

ASJC Scopus subject areas

  • Health Policy

Cite this

Lagu, T., Weiner, M. G., Eachus, S., Tang, S. S. K., Schwartz, J. S., & Turner, B. J. (2009). Effect of patient comorbidities on filling of antihypertensive prescriptions. American Journal of Managed Care, 15(1), 24-30.

Effect of patient comorbidities on filling of antihypertensive prescriptions. / Lagu, Tara; Weiner, Mark G.; Eachus, Susan; Tang, Simon S K; Schwartz, J. Sanford; Turner, Barbara J.

In: American Journal of Managed Care, Vol. 15, No. 1, 01.2009, p. 24-30.

Research output: Contribution to journalArticle

Lagu, T, Weiner, MG, Eachus, S, Tang, SSK, Schwartz, JS & Turner, BJ 2009, 'Effect of patient comorbidities on filling of antihypertensive prescriptions', American Journal of Managed Care, vol. 15, no. 1, pp. 24-30.
Lagu T, Weiner MG, Eachus S, Tang SSK, Schwartz JS, Turner BJ. Effect of patient comorbidities on filling of antihypertensive prescriptions. American Journal of Managed Care. 2009 Jan;15(1):24-30.
Lagu, Tara ; Weiner, Mark G. ; Eachus, Susan ; Tang, Simon S K ; Schwartz, J. Sanford ; Turner, Barbara J. / Effect of patient comorbidities on filling of antihypertensive prescriptions. In: American Journal of Managed Care. 2009 ; Vol. 15, No. 1. pp. 24-30.
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