Abstract
The effect of mercuric chloride at two different doses, 0.5 mg/kg body weight (low dose), 1 mg/kg body weight (high dose), for 30 days, was seen on the circulating hormones in the mature male albino rats. Testosterone level was markedly decreased in the low dose (P< 0.01) and high dose (P< 0.001) treated animals. The level of luteinizing hormone (LH) was also reduced in the low dose (P< 0.01) as well as in the high dose (P< 0.001) treated animals. However, follicle stimulating hormone (FSH) and prolactin (PRL) levels were found to be decreased only in the high dose (P< 0.05) treated animals and no change was observed in the low dose. treated animals. The changes in the hormone levels caused by the mercuric chloride treatment suggest the dysfunction of pituitary-testicular axis.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 401-404 |
| Number of pages | 4 |
| Journal | Journal of Environmental Biology |
| Volume | 24 |
| Issue number | 4 |
| State | Published - Oct 2003 |
| Externally published | Yes |
Keywords
- FSH
- LH
- Mercuric chloride
- Prolactin
- Rat
- Testosterone
ASJC Scopus subject areas
- Environmental Engineering
- Toxicology
- Health, Toxicology and Mutagenesis