Effect of irradiation on the maturation of Wilms' tumor

George A. Bannayan; Andrew G. Huvos; Giulio J. D'Angio

doi:10.1002/1097-0142(197104)27:4<812::AID-CNCR2820270409>3.0.CO;2-E

Effect of irradiation on the maturation of Wilms' tumor

George A. Bannayan, Andrew G. Huvos, Giulio J. D'Angio

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57 Scopus citations

Abstract

A study was undertaken to ascertain the morphological differences that exist between the primary tumor and the metastatic deposits of 55 selected cases of Wilms' tumors. The observations in this study point towards a greater degree of non‐epithelial differentiation and a decrease in the tubular and glomerular differentiation in the metastases as compared to the primary tumors. The study also suggests that irradiation accelerates and possibly induces non‐epithelial differentiation.

Original language	English (US)
Pages (from-to)	812-818
Number of pages	7
Journal	Cancer
Volume	27
Issue number	4
DOIs	https://doi.org/10.1002/1097-0142(197104)27:4<812::AID-CNCR2820270409>3.0.CO;2-E
State	Published - Apr 1971
Externally published	Yes

ASJC Scopus subject areas

Oncology
Cancer Research

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10.1002/1097-0142(197104)27:4<812::AID-CNCR2820270409>3.0.CO;2-E

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AB - A study was undertaken to ascertain the morphological differences that exist between the primary tumor and the metastatic deposits of 55 selected cases of Wilms' tumors. The observations in this study point towards a greater degree of non‐epithelial differentiation and a decrease in the tubular and glomerular differentiation in the metastases as compared to the primary tumors. The study also suggests that irradiation accelerates and possibly induces non‐epithelial differentiation.

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Effect of irradiation on the maturation of Wilms' tumor

Abstract

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