Effect of irradiation on the maturation of Wilms' tumor

George A. Bannayan, Andrew G. Huvos, Giulio J. D'Angio

Research output: Contribution to journalArticle

57 Scopus citations

Abstract

A study was undertaken to ascertain the morphological differences that exist between the primary tumor and the metastatic deposits of 55 selected cases of Wilms' tumors. The observations in this study point towards a greater degree of non‐epithelial differentiation and a decrease in the tubular and glomerular differentiation in the metastases as compared to the primary tumors. The study also suggests that irradiation accelerates and possibly induces non‐epithelial differentiation.

Original languageEnglish (US)
Pages (from-to)812-818
Number of pages7
JournalCancer
Volume27
Issue number4
DOIs
StatePublished - Apr 1971
Externally publishedYes

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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