Effect of intraluminal PGE<inf>2</inf> and systemic indomethacin on sodium chloride transport in the rat distal tubule

R. T. Kunau, C. Geiger, J. Hull, R. M. Wong-Garcia

Research output: Contribution to journalArticle

Abstract

The present stuies examined the effect of intraluminal PGE<inf>2</inf> and systemic indomethacin on sodium chloride transport in the superficial distal tubule of the rat nephron. Controlled quantities of sodium chloride delivery to this segment were provided by in vivo microperfusion techniques. Neither 2μm intraluminal PGE<inf>2</inf> 2 mg/kg body weight indomethacin given intravenously nor the combination of these agents affected sodium chloride transport in this nephron segment.

Original languageEnglish (US)
Pages (from-to)105-111
Number of pages7
JournalKidney and Blood Pressure Research
Volume6
Issue number3
StatePublished - 1983

Keywords

  • Distal tubule
  • Indomethacin
  • PGE<inf>2</inf>
  • Sodium transport

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Nephrology

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