Effect of internal mammary vessels radiation dose on outcomes of free flap breast reconstruction

Orit Kaidar-Person, Michael J. Eblan, Joseph M. Caster, Amita R. Shah, David Fried, Lawrence B. Marks, Clara N. Lee, Ellen L. Jones

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

To assess the impact of internal mammary (IM) vessels radiation dose on autologous free-flap based breast reconstruction outcomes. We retrospectively evaluated the medical records of breast cancer patients who underwent mastectomy and free-flap breast reconstruction after postoperative radiation therapy (RT) to the breast/chest wall with (n = 9) or without (n = 11) electively including the IM lymph nodes. Twenty patients were included. Median age at diagnosis was 50 years (range, 33-63). The median time interval between the start of RT and reconstructive surgery was 16 months (range, 6-45). The maximal IM vessels dose was not associated with the risk of all complications (P = 0.44) or fat necrosis (P = 0.31). The mean IM vessels dose was not significant for the risk of all complications (P = 0.13) but was significant for fat necrosis (P = 0.04). A high mean IM vessels dose was related to the occurrence of fat necrosis.

Original languageEnglish (US)
Pages (from-to)286-289
Number of pages4
JournalBreast Journal
Volume25
Issue number2
DOIs
StatePublished - Mar 1 2019

Keywords

  • breast cancer
  • complications
  • dose
  • flap
  • internal mammary vessels
  • radiation therapy
  • reconstruction

ASJC Scopus subject areas

  • Internal Medicine
  • Surgery
  • Oncology

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