Abstract
To assess the impact of internal mammary (IM) vessels radiation dose on autologous free-flap based breast reconstruction outcomes. We retrospectively evaluated the medical records of breast cancer patients who underwent mastectomy and free-flap breast reconstruction after postoperative radiation therapy (RT) to the breast/chest wall with (n = 9) or without (n = 11) electively including the IM lymph nodes. Twenty patients were included. Median age at diagnosis was 50 years (range, 33-63). The median time interval between the start of RT and reconstructive surgery was 16 months (range, 6-45). The maximal IM vessels dose was not associated with the risk of all complications (P = 0.44) or fat necrosis (P = 0.31). The mean IM vessels dose was not significant for the risk of all complications (P = 0.13) but was significant for fat necrosis (P = 0.04). A high mean IM vessels dose was related to the occurrence of fat necrosis.
Original language | English (US) |
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Pages (from-to) | 286-289 |
Number of pages | 4 |
Journal | Breast Journal |
Volume | 25 |
Issue number | 2 |
DOIs | |
State | Published - Mar 1 2019 |
Keywords
- breast cancer
- complications
- dose
- flap
- internal mammary vessels
- radiation therapy
- reconstruction
ASJC Scopus subject areas
- Internal Medicine
- Surgery
- Oncology