Effect of errors in reangulation on planar and tomographic thallium-201 washout profile curves

J. L. Lancaster, M. R. Starling, D. T. Kopp, J. C. Lasher, R. Blumhardt

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

Cardiac phantom studies were performed with and without a defect present to test the hypothesis that myocardial 201Tl quantitative circumferential washout profile curves calculated from planar and rotating slant hole (RSH) collimator tomographic images are equally affected by errors in axial repositioning. Simulated stress images were acquired with the long axis of the phantom perpendicular to the camera surface and redistribution images were acquired to represent 50% 201Tl washout with axial repositioning errors relative to the stress position ranging from 0 to 20° in 5° increments. There was a decrease in the 201Tl washout profile curves compared to that expected (50%) in the wall tilted away from the camera surface, and a reciprocal increase in the 201Tl washout profile curves in the wall tilted towards the camera surface for both imaging techniques whether a lesion was present or not. This effect became more pronounced as the error in axial repositioning was increased for both the planar (p < 0.001) and the RSH tomographic (p < 0.001) techniques. However, the deviation of the 201Tl washout profile curves from that expected (50%) was greater for the planar imaging technqiue with or without a lesion (p < 0.05 to 0.001). Thus, we conclude that 201Tl quantitative circumferential washout profile curves calculated using this tomographic imaging technique are less affected by errors in axial repositioning than those calculated using an equivalent projection by standard planar imaging method. These data emphasize the importance which must be placed on the repositioning of patients to obtain valid 201Tl washout profile curves for detection and localization of coronary artery disease.

Original languageEnglish (US)
Pages (from-to)1445-1455
Number of pages11
JournalJournal of Nuclear Medicine
Volume26
Issue number12
StatePublished - 1985

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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