Abstract
Effect of catheter eccentricity on the appearance of stent struts in IV-OCT images in presence of thick neointimas was examined by simulation of light-stent interaction. A phantom blood vessel was constructed from a mix of polydimethylsiloxane (PDMS) and titanium dioxide to simulate the elastic and optical scattering properties of the arterial wall. A Cordis CYPHER ® sirolimus-eluting stent was deployed within the phantom vessel and high resolution Micro-CT images of the stent strut were recorded to create a three-dimensional representation. Simulation of IV-OCT catheter and reflection of light from the stent strut and neointima was implemented for different catheter eccentricities. An optical model of the IV-OCT catheter was constructed and IV-OCT images corresponding to rotation of the light beam over the stent strut were simulated. The measured parameters included intensity and optical path length of light reflecting from the stent strut and coupled into catheter. The results indicate that in presence of thick neointimas sunflower effect is not observed and neointimal thickness measurement using IV-OCT is consistent with true values irrespective of catheter eccentricity.
| Original language | English (US) |
|---|---|
| Title of host publication | Progress in Biomedical Optics and Imaging - Proceedings of SPIE |
| Volume | 8565 |
| DOIs | |
| State | Published - 2013 |
| Externally published | Yes |
| Event | Photonic Therapeutics and Diagnostics IX - San Francisco, CA, United States Duration: Feb 2 2013 → Feb 7 2013 |
Other
| Other | Photonic Therapeutics and Diagnostics IX |
|---|---|
| Country | United States |
| City | San Francisco, CA |
| Period | 2/2/13 → 2/7/13 |
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Keywords
- Artifact
- IV-OCT
- Neointima
- Stent
ASJC Scopus subject areas
- Atomic and Molecular Physics, and Optics
- Electronic, Optical and Magnetic Materials
- Biomaterials
- Radiology Nuclear Medicine and imaging
Cite this
Effect of catheter eccentricity on appearance of stent struts in IV-OCT images in presence of thick neointimas. / Elahi, Sahar; Feldman, Marc D; Dijkstra, Jouke; Milner, Thomas E.
Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 8565 2013. 856540.Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
}
TY - GEN
T1 - Effect of catheter eccentricity on appearance of stent struts in IV-OCT images in presence of thick neointimas
AU - Elahi, Sahar
AU - Feldman, Marc D
AU - Dijkstra, Jouke
AU - Milner, Thomas E.
PY - 2013
Y1 - 2013
N2 - Effect of catheter eccentricity on the appearance of stent struts in IV-OCT images in presence of thick neointimas was examined by simulation of light-stent interaction. A phantom blood vessel was constructed from a mix of polydimethylsiloxane (PDMS) and titanium dioxide to simulate the elastic and optical scattering properties of the arterial wall. A Cordis CYPHER ® sirolimus-eluting stent was deployed within the phantom vessel and high resolution Micro-CT images of the stent strut were recorded to create a three-dimensional representation. Simulation of IV-OCT catheter and reflection of light from the stent strut and neointima was implemented for different catheter eccentricities. An optical model of the IV-OCT catheter was constructed and IV-OCT images corresponding to rotation of the light beam over the stent strut were simulated. The measured parameters included intensity and optical path length of light reflecting from the stent strut and coupled into catheter. The results indicate that in presence of thick neointimas sunflower effect is not observed and neointimal thickness measurement using IV-OCT is consistent with true values irrespective of catheter eccentricity.
AB - Effect of catheter eccentricity on the appearance of stent struts in IV-OCT images in presence of thick neointimas was examined by simulation of light-stent interaction. A phantom blood vessel was constructed from a mix of polydimethylsiloxane (PDMS) and titanium dioxide to simulate the elastic and optical scattering properties of the arterial wall. A Cordis CYPHER ® sirolimus-eluting stent was deployed within the phantom vessel and high resolution Micro-CT images of the stent strut were recorded to create a three-dimensional representation. Simulation of IV-OCT catheter and reflection of light from the stent strut and neointima was implemented for different catheter eccentricities. An optical model of the IV-OCT catheter was constructed and IV-OCT images corresponding to rotation of the light beam over the stent strut were simulated. The measured parameters included intensity and optical path length of light reflecting from the stent strut and coupled into catheter. The results indicate that in presence of thick neointimas sunflower effect is not observed and neointimal thickness measurement using IV-OCT is consistent with true values irrespective of catheter eccentricity.
KW - Artifact
KW - IV-OCT
KW - Neointima
KW - Stent
UR - http://www.scopus.com/inward/record.url?scp=84878171796&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84878171796&partnerID=8YFLogxK
U2 - 10.1117/12.2005668
DO - 10.1117/12.2005668
M3 - Conference contribution
AN - SCOPUS:84878171796
SN - 9780819493347
VL - 8565
BT - Progress in Biomedical Optics and Imaging - Proceedings of SPIE
ER -