Effect of catheter eccentricity on appearance of stent struts in IV-OCT images in presence of thick neointimas

Sahar Elahi, Marc D Feldman, Jouke Dijkstra, Thomas E. Milner

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Effect of catheter eccentricity on the appearance of stent struts in IV-OCT images in presence of thick neointimas was examined by simulation of light-stent interaction. A phantom blood vessel was constructed from a mix of polydimethylsiloxane (PDMS) and titanium dioxide to simulate the elastic and optical scattering properties of the arterial wall. A Cordis CYPHER ® sirolimus-eluting stent was deployed within the phantom vessel and high resolution Micro-CT images of the stent strut were recorded to create a three-dimensional representation. Simulation of IV-OCT catheter and reflection of light from the stent strut and neointima was implemented for different catheter eccentricities. An optical model of the IV-OCT catheter was constructed and IV-OCT images corresponding to rotation of the light beam over the stent strut were simulated. The measured parameters included intensity and optical path length of light reflecting from the stent strut and coupled into catheter. The results indicate that in presence of thick neointimas sunflower effect is not observed and neointimal thickness measurement using IV-OCT is consistent with true values irrespective of catheter eccentricity.

Original languageEnglish (US)
Title of host publicationProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume8565
DOIs
StatePublished - 2013
Externally publishedYes
EventPhotonic Therapeutics and Diagnostics IX - San Francisco, CA, United States
Duration: Feb 2 2013Feb 7 2013

Other

OtherPhotonic Therapeutics and Diagnostics IX
CountryUnited States
CitySan Francisco, CA
Period2/2/132/7/13

Fingerprint

struts
Stents
Catheters
Struts
eccentricity
Light
sunflowers
blood vessels
optical paths
light beams
titanium oxides
Neointima
vessels
Thickness measurement
Helianthus
elastic scattering
Blood vessels
simulation
Polydimethylsiloxane
Sirolimus

Keywords

  • Artifact
  • IV-OCT
  • Neointima
  • Stent

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics
  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

Cite this

Elahi, S., Feldman, M. D., Dijkstra, J., & Milner, T. E. (2013). Effect of catheter eccentricity on appearance of stent struts in IV-OCT images in presence of thick neointimas. In Progress in Biomedical Optics and Imaging - Proceedings of SPIE (Vol. 8565). [856540] https://doi.org/10.1117/12.2005668

Effect of catheter eccentricity on appearance of stent struts in IV-OCT images in presence of thick neointimas. / Elahi, Sahar; Feldman, Marc D; Dijkstra, Jouke; Milner, Thomas E.

Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 8565 2013. 856540.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Elahi, S, Feldman, MD, Dijkstra, J & Milner, TE 2013, Effect of catheter eccentricity on appearance of stent struts in IV-OCT images in presence of thick neointimas. in Progress in Biomedical Optics and Imaging - Proceedings of SPIE. vol. 8565, 856540, Photonic Therapeutics and Diagnostics IX, San Francisco, CA, United States, 2/2/13. https://doi.org/10.1117/12.2005668
Elahi S, Feldman MD, Dijkstra J, Milner TE. Effect of catheter eccentricity on appearance of stent struts in IV-OCT images in presence of thick neointimas. In Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 8565. 2013. 856540 https://doi.org/10.1117/12.2005668
Elahi, Sahar ; Feldman, Marc D ; Dijkstra, Jouke ; Milner, Thomas E. / Effect of catheter eccentricity on appearance of stent struts in IV-OCT images in presence of thick neointimas. Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 8565 2013.
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