Effect of brief vascular perfusion on the ultrastructure and activity of mitochondria isolated from the rat heart

J. L. Staecker; M. J. Nadakavukaren; A. Richardson

doi:10.1007/BF00217581

Effect of brief vascular perfusion on the ultrastructure and activity of mitochondria isolated from the rat heart

J. L. Staecker, M. J. Nadakavukaren, A. Richardson

Barshop Institute

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Mitochondria isolated from heart tissue after a 1-min perfusion with Hanks medium were found to have significantly lower rates of State-3 respiration and respiratory control ratios compared to mitochondria isolated from non-perfused hearts. Examination of the mitochondrial preparations by electron microscopy revealed that a large proportion of the mitochondria isolated from perfused heart tissue were swollen and broken compared to mitochondria from non-perfused hearts.

Original language	English (US)
Pages (from-to)	247-249
Number of pages	3
Journal	Cell and Tissue Research
Volume	240
Issue number	1
DOIs	https://doi.org/10.1007/BF00217581
State	Published - Apr 1985

Keywords

Heart
Mitochondria
Perfusion
Rat
Ultrastructure

ASJC Scopus subject areas

Pathology and Forensic Medicine
Histology
Cell Biology

Access to Document

10.1007/BF00217581

Cite this

@article{0664573bc5f94caa8dea5d606a7581bd,

title = "Effect of brief vascular perfusion on the ultrastructure and activity of mitochondria isolated from the rat heart",

abstract = "Mitochondria isolated from heart tissue after a 1-min perfusion with Hanks medium were found to have significantly lower rates of State-3 respiration and respiratory control ratios compared to mitochondria isolated from non-perfused hearts. Examination of the mitochondrial preparations by electron microscopy revealed that a large proportion of the mitochondria isolated from perfused heart tissue were swollen and broken compared to mitochondria from non-perfused hearts.",

keywords = "Heart, Mitochondria, Perfusion, Rat, Ultrastructure",

author = "Staecker, {J. L.} and Nadakavukaren, {M. J.} and A. Richardson",

year = "1985",

month = apr,

doi = "10.1007/BF00217581",

language = "English (US)",

volume = "240",

pages = "247--249",

journal = "Zeitschrift für Zellforschung und mikroskopische Anatomie (Vienna, Austria : 1948)",

issn = "0302-766X",

publisher = "Springer Verlag",

number = "1",

}

TY - JOUR

T1 - Effect of brief vascular perfusion on the ultrastructure and activity of mitochondria isolated from the rat heart

AU - Staecker, J. L.

AU - Nadakavukaren, M. J.

AU - Richardson, A.

PY - 1985/4

Y1 - 1985/4

N2 - Mitochondria isolated from heart tissue after a 1-min perfusion with Hanks medium were found to have significantly lower rates of State-3 respiration and respiratory control ratios compared to mitochondria isolated from non-perfused hearts. Examination of the mitochondrial preparations by electron microscopy revealed that a large proportion of the mitochondria isolated from perfused heart tissue were swollen and broken compared to mitochondria from non-perfused hearts.

AB - Mitochondria isolated from heart tissue after a 1-min perfusion with Hanks medium were found to have significantly lower rates of State-3 respiration and respiratory control ratios compared to mitochondria isolated from non-perfused hearts. Examination of the mitochondrial preparations by electron microscopy revealed that a large proportion of the mitochondria isolated from perfused heart tissue were swollen and broken compared to mitochondria from non-perfused hearts.

KW - Heart

KW - Mitochondria

KW - Perfusion

KW - Rat

KW - Ultrastructure

UR - http://www.scopus.com/inward/record.url?scp=0021902446&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0021902446&partnerID=8YFLogxK

U2 - 10.1007/BF00217581

DO - 10.1007/BF00217581

M3 - Article

C2 - 3995543

AN - SCOPUS:0021902446

VL - 240

SP - 247

EP - 249

JO - Zeitschrift für Zellforschung und mikroskopische Anatomie (Vienna, Austria : 1948)

JF - Zeitschrift für Zellforschung und mikroskopische Anatomie (Vienna, Austria : 1948)

SN - 0302-766X

IS - 1

ER -

Effect of brief vascular perfusion on the ultrastructure and activity of mitochondria isolated from the rat heart

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this