Effect of brief vascular perfusion on the ultrastructure and activity of mitochondria isolated from the rat heart

J. L. Staecker; M. J. Nadakavukaren; A. Richardson

doi:10.1007/BF00217581

Effect of brief vascular perfusion on the ultrastructure and activity of mitochondria isolated from the rat heart

J. L. Staecker, M. J. Nadakavukaren, A. Richardson

Barshop Institute

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Mitochondria isolated from heart tissue after a 1-min perfusion with Hanks medium were found to have significantly lower rates of State-3 respiration and respiratory control ratios compared to mitochondria isolated from non-perfused hearts. Examination of the mitochondrial preparations by electron microscopy revealed that a large proportion of the mitochondria isolated from perfused heart tissue were swollen and broken compared to mitochondria from non-perfused hearts.

Original language	English (US)
Pages (from-to)	247-249
Number of pages	3
Journal	Cell and Tissue Research
Volume	240
Issue number	1
DOIs	https://doi.org/10.1007/BF00217581
State	Published - Apr 1985

Keywords

Heart
Mitochondria
Perfusion
Rat
Ultrastructure

ASJC Scopus subject areas

Pathology and Forensic Medicine
Histology
Cell Biology

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10.1007/BF00217581

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