Abstract
We aimed to assess the effect of bilateral oophorectomy on vaginal wound healing in three groups of New Zealand White rabbits (24 rabbits each). Group 1 underwent bilateral oophorectomy, group 2 underwent a sham surgery, and group 3 served as control. Standardized vaginal tissue specimens were harvested and assessed for wound and scar surface area and tensiometric analysis before wounding, and sequentially thereafter, showing that vaginal wound closure, scar contraction, and recovery of biomechanical properties are significantly slower in oophorectomized rabbits.
Original language | English (US) |
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Pages (from-to) | 1467-1470 |
Number of pages | 4 |
Journal | Fertility and sterility |
Volume | 95 |
Issue number | 4 |
DOIs | |
State | Published - Mar 15 2011 |
Externally published | Yes |
Keywords
- Biomechanical properties
- Young's modulus
- estrogen deficiency
- menopause
- oophorectomy
- tensile energy
- tensile strength
- vagina
- wound healing
ASJC Scopus subject areas
- Reproductive Medicine
- Obstetrics and Gynecology