Eclampsia complicating hydatidiform molar pregnancy with a coexisting, viable fetus: A case report

Patrick S. Ramsey, Jo T. Van Winter, Thomas A. Gaffey, Kirk D. Ramin

Research output: Contribution to journalArticlepeer-review

9 Scopus citations


BACKGROUND: Eclampsia is a rare and serious complication of pregnancy. The occurrence of preeclampsia prior to the 20th week of gestation has been associated with concurrent hydatidiform molar pregnancy. We present a case of eclampsia complicating a partial molar pregnancy associated with a viable fetus. CASE: A 22-year-old white woman, gravida 1, para 0, at 14 weeks' gestation, presented with an excruciating headache associated with hypertension, proteinuria and a viable intrauterine fetus with gastroschisis. Subsequently the patient had a generalized tonic-clonic seizure which resolved with magnesium sulfate therapy. Markedly elevated quantitative human chorionic gonadotropin and a moderately thickened placenta were the sole clinical features suggestive of a molar gestation. Dilation and evacuation was performed revealing unremarkable products of conception. Pathologic and cytogenetic analyses revealed a triploid fetus (69,XXX) consistent with partial molar pregnancy. CONCLUSION: Development of preeclampsia/eclampsia prior to 20 weeks of gestation should prompt a clinical evaluation to exclude the possibility of an underlying hydatidiform molar pregnancy.

Original languageEnglish (US)
Pages (from-to)456-458
Number of pages3
JournalJournal of Reproductive Medicine for the Obstetrician and Gynecologist
Issue number5
StatePublished - May 1998
Externally publishedYes


  • Eclampsia
  • Hydatidiform mole
  • Placenta

ASJC Scopus subject areas

  • Reproductive Medicine
  • Obstetrics and Gynecology


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