Early and Late Complications Following Dynamic Stereotactic Radiosurgery and Fractionated Stereotactic Radiotherapy

R. Mc Kenzie Michal, Sohami Luis, Caron Jean-Louis, Oliver Andre, Villemure Jean-Guy, B. Podgorsak Ervin

Research output: Contribution to journalArticlepeer-review

19 Scopus citations

Abstract

Between December 1986 and June 1990, 112 patients (116 lesions), underwent treatment with dynamic stereotactic radiosurgery at McGill University. Of the treated lesions, 59 were arteriovenous malformations and 53 were a variety of other neoplastic or non-neoplastic conditions. In 86 lesions, the treatment was delivered in a single fraction and the treatment of the remaining 30 lesions was fractionated. Complications attributed to treatment developed in seven of the 112 patients (6.3%). No relationship was found between complications and prescribed dose, fractionation, collimator diameter, type and anatomical region of the lesion that was treated, or previous irradiation. Although extensive clinical experience will be necessary to determine optimal total doses, the potential role of fractionated treatment, and the tolerance of critical structures to radiosurgery, the relatively low incidence of complications in our series allows us to conclude that radiosurgery is well tolerated by the vast majority of patients.

Original languageEnglish (US)
Pages (from-to)279-285
Number of pages7
JournalCanadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques
Volume20
Issue number4
DOIs
StatePublished - Nov 1993

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

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