Early and late complications following dynamic stereotactic radiosurgery and fractionated stereotactic radiotherapy

M. R. McKenzie, L. Souhami, Jean-louis R Caron, A. Olivier, J. G. Villemure, E. B. Podgorsak

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Between December 1986 and June 1990, 112 patients (116 lesions), underwent treatment with dynamic stereotactic radiosurgery at McGill University. Of the treated lesions, 59 were arteriovenous malformations and 53 were a variety of other neoplastic or non-neoplastic conditions. In 86 lesions, the treatment was delivered in a single fraction and the treatment of the remaining 30 lesions was fractionated. Complications attributed to treatment developed in seven of the 112 patients (6.3%). No relationship was found between complications and prescribed dose, fractionation, collimator diameter, type and anatomical region of the lesion that was treated, or previous irradiation. Although extensive clinical experience will be necessary to determine optimal total doses, the potential role of fractionated treatment, and the tolerance of critical structures to radiosurgery, the relatively low incidence of complications in our series allows us to conclude that radiosurgery is well tolerated by the vast majority of patients.

Original languageEnglish (US)
Pages (from-to)279-285
Number of pages7
JournalCanadian Journal of Neurological Sciences
Volume20
Issue number4
StatePublished - 1993
Externally publishedYes

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Radiosurgery
Radiotherapy
Dose Fractionation
Therapeutics
Arteriovenous Malformations
Incidence

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

Cite this

McKenzie, M. R., Souhami, L., Caron, J. R., Olivier, A., Villemure, J. G., & Podgorsak, E. B. (1993). Early and late complications following dynamic stereotactic radiosurgery and fractionated stereotactic radiotherapy. Canadian Journal of Neurological Sciences, 20(4), 279-285.

Early and late complications following dynamic stereotactic radiosurgery and fractionated stereotactic radiotherapy. / McKenzie, M. R.; Souhami, L.; Caron, Jean-louis R; Olivier, A.; Villemure, J. G.; Podgorsak, E. B.

In: Canadian Journal of Neurological Sciences, Vol. 20, No. 4, 1993, p. 279-285.

Research output: Contribution to journalArticle

McKenzie, MR, Souhami, L, Caron, JR, Olivier, A, Villemure, JG & Podgorsak, EB 1993, 'Early and late complications following dynamic stereotactic radiosurgery and fractionated stereotactic radiotherapy', Canadian Journal of Neurological Sciences, vol. 20, no. 4, pp. 279-285.
McKenzie, M. R. ; Souhami, L. ; Caron, Jean-louis R ; Olivier, A. ; Villemure, J. G. ; Podgorsak, E. B. / Early and late complications following dynamic stereotactic radiosurgery and fractionated stereotactic radiotherapy. In: Canadian Journal of Neurological Sciences. 1993 ; Vol. 20, No. 4. pp. 279-285.
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