TY - JOUR
T1 - Dynamic covariation of symptoms of anxiety and depression among newly-diagnosed patients with major depressive episode, panic disorder, and controls
AU - Katerndahl, David
AU - Wang, Chen Pin
PY - 2007/7
Y1 - 2007/7
N2 - The purpose of this study was to explore the relationship between the dynamics of symptoms of anxiety and depression in primary care patients with newly-diagnosed major depressive episode (MDE), panic disorder, and neither disorder. Five adult patients presenting each with MDE, panic disorder, and neither disorder were recruited from two primary care clinics. Hourly self-assessments of levels of anxiety and depression were made for a 30-day period. Using differential structural equation modeling analysis, MDE and panic disorder differed from controls, but not from each other, in symptom levels, covariability, and effect on depression acceleration. Using state space grid analysis, attractors in controls were larger, more "influential", and more consistent. Patients with MDE had more total attractors but less consistent Week 1 attractors than patients with panic disorder or controls, suggesting more transient and less stable dynamics. This exploratory study suggests the importance of looking at covariability of anxiety and depression in mental illness.
AB - The purpose of this study was to explore the relationship between the dynamics of symptoms of anxiety and depression in primary care patients with newly-diagnosed major depressive episode (MDE), panic disorder, and neither disorder. Five adult patients presenting each with MDE, panic disorder, and neither disorder were recruited from two primary care clinics. Hourly self-assessments of levels of anxiety and depression were made for a 30-day period. Using differential structural equation modeling analysis, MDE and panic disorder differed from controls, but not from each other, in symptom levels, covariability, and effect on depression acceleration. Using state space grid analysis, attractors in controls were larger, more "influential", and more consistent. Patients with MDE had more total attractors but less consistent Week 1 attractors than patients with panic disorder or controls, suggesting more transient and less stable dynamics. This exploratory study suggests the importance of looking at covariability of anxiety and depression in mental illness.
KW - Anxiety
KW - Depression
KW - Nonlinear dynamics
KW - Panic disorder
KW - Variability
UR - http://www.scopus.com/inward/record.url?scp=34547316537&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=34547316537&partnerID=8YFLogxK
M3 - Article
C2 - 17572989
AN - SCOPUS:34547316537
SN - 1090-0578
VL - 11
SP - 349
EP - 365
JO - Nonlinear dynamics, psychology, and life sciences
JF - Nonlinear dynamics, psychology, and life sciences
IS - 3
ER -