Duplication within the haptoglobin Hp2 gene

Nobuyo Maeda; Funmei Yang; Don R. Barnett; Barbara H. Bowman; Oliver Smithies

doi:10.1038/309131a0

Duplication within the haptoglobin Hp² gene

Nobuyo Maeda, Funmei Yang, Don R. Barnett, Barbara H. Bowman, Oliver Smithies

Department of Cell Systems & Anatomy

Research output: Contribution to journal › Short survey › peer-review

169 Scopus citations

Abstract

DNA sequencing shows that the intragenic duplication within the human haptoglobin Hp² allele was formed by a non-homologous, probably random, crossing-over within different introns of two Hp¹genes, probably in an Hp^1F/Hp^1S heterozygote.

Original language	English (US)
Pages (from-to)	131-135
Number of pages	5
Journal	Nature
Volume	309
Issue number	5964
DOIs	https://doi.org/10.1038/309131a0
State	Published - 1984

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@article{82bc9a3f61a74211bde49507f1f7ea84,

title = "Duplication within the haptoglobin Hp2 gene",

abstract = "DNA sequencing shows that the intragenic duplication within the human haptoglobin Hp2 allele was formed by a non-homologous, probably random, crossing-over within different introns of two Hp1genes, probably in an Hp1F/Hp1S heterozygote.",

author = "Nobuyo Maeda and Funmei Yang and Barnett, {Don R.} and Bowman, {Barbara H.} and Oliver Smithies",

year = "1984",

doi = "10.1038/309131a0",

language = "English (US)",

volume = "309",

pages = "131--135",

journal = "Nature",

issn = "0028-0836",

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T1 - Duplication within the haptoglobin Hp2 gene

AU - Maeda, Nobuyo

AU - Yang, Funmei

AU - Barnett, Don R.

AU - Bowman, Barbara H.

AU - Smithies, Oliver

PY - 1984

Y1 - 1984

N2 - DNA sequencing shows that the intragenic duplication within the human haptoglobin Hp2 allele was formed by a non-homologous, probably random, crossing-over within different introns of two Hp1genes, probably in an Hp1F/Hp1S heterozygote.

AB - DNA sequencing shows that the intragenic duplication within the human haptoglobin Hp2 allele was formed by a non-homologous, probably random, crossing-over within different introns of two Hp1genes, probably in an Hp1F/Hp1S heterozygote.

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U2 - 10.1038/309131a0

DO - 10.1038/309131a0

M3 - Short survey

C2 - 6325933

AN - SCOPUS:0021288584

VL - 309

SP - 131

EP - 135

JO - Nature

JF - Nature

SN - 0028-0836

IS - 5964

ER -

Duplication within the haptoglobin Hp² gene

Abstract

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