Drug loading of nanoporous TiO2 films

Arturo A. Ayon; Michael Cantu; Kalpana Chava; C. Mauli Agrawal; Marc D. Feldman; Dave Johnson; Devang Patel; Denes Marton; Emily Shi

doi:10.1088/1748-6041/1/4/L01

Drug loading of nanoporous TiO₂ films

Arturo A. Ayon, Michael Cantu, Kalpana Chava, C. Mauli Agrawal, Marc D. Feldman, Dave Johnson, Devang Patel, Denes Marton, Emily Shi

Research output: Contribution to journal › Article › peer-review

43 Scopus citations

Abstract

The loading of therapeutic amounts of drug on a nanoporous TiO₂ surface is described. This novel drug-loading scheme on a biocompatible surface, when employed on medical implants, will benefit patients who require the deployment of drug-eluting implants. Anticoagulants, analgesics and antibiotics can be considered on the associated implants for drug delivery during the time of maximal pain or risk for patients undergoing orthopedic procedures. Therefore, this scheme will maximize the chances of patient recovery.

Original language	English (US)
Article number	L01
Pages (from-to)	L11-L15
Journal	Biomedical Materials
Volume	1
Issue number	4
DOIs	https://doi.org/10.1088/1748-6041/1/4/L01
State	Published - Dec 1 2006

ASJC Scopus subject areas

Bioengineering
Biomaterials
Biomedical Engineering

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AU - Chava, Kalpana

AU - Agrawal, C. Mauli

AU - Feldman, Marc D.

AU - Johnson, Dave

AU - Patel, Devang

AU - Marton, Denes

AU - Shi, Emily

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AB - The loading of therapeutic amounts of drug on a nanoporous TiO2 surface is described. This novel drug-loading scheme on a biocompatible surface, when employed on medical implants, will benefit patients who require the deployment of drug-eluting implants. Anticoagulants, analgesics and antibiotics can be considered on the associated implants for drug delivery during the time of maximal pain or risk for patients undergoing orthopedic procedures. Therefore, this scheme will maximize the chances of patient recovery.

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