Dopaminergic mediation of reward: Evidence gained using a natural reinforcer in a behavioral contrast paradigm

D. R. Royall; W. R. Klemm

doi:10.1016/0304-3940(81)90386-4

Dopaminergic mediation of reward: Evidence gained using a natural reinforcer in a behavioral contrast paradigm

D. R. Royall, W. R. Klemm

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Abstract

Previous studies suggest a dopaminergic basis for the apparent reward properties of self-stimulation of certain brain areas with electrical current. The data of this present study indicate that there may be a dopaminergic role in the perceived hedonic quality of natural reinforcers. Using a classical behavioral contrast paradigm, we observed in rats that the perceived reward of a saccharin solution was decreased by haloperidol and increased by apomorphine, in doses that did not cause non-specific performance effects.

Original language	English (US)
Pages (from-to)	223-229
Number of pages	7
Journal	Neuroscience Letters
Volume	21
Issue number	2
DOIs	https://doi.org/10.1016/0304-3940(81)90386-4
State	Published - Jan 20 1981
Externally published	Yes

ASJC Scopus subject areas

General Neuroscience

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Dopaminergic mediation of reward: Evidence gained using a natural reinforcer in a behavioral contrast paradigm

Abstract

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