Dopaminergic mediation of reward: Evidence gained using a natural reinforcer in a behavioral contrast paradigm

D. R. Royall, W. R. Klemm

Research output: Contribution to journalArticle

16 Scopus citations

Abstract

Previous studies suggest a dopaminergic basis for the apparent reward properties of self-stimulation of certain brain areas with electrical current. The data of this present study indicate that there may be a dopaminergic role in the perceived hedonic quality of natural reinforcers. Using a classical behavioral contrast paradigm, we observed in rats that the perceived reward of a saccharin solution was decreased by haloperidol and increased by apomorphine, in doses that did not cause non-specific performance effects.

Original languageEnglish (US)
Pages (from-to)223-229
Number of pages7
JournalNeuroscience Letters
Volume21
Issue number2
DOIs
StatePublished - Jan 20 1981
Externally publishedYes

ASJC Scopus subject areas

  • Neuroscience(all)

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