DNA Directed Pro-Dopamine Regulation Coupling Subluxation Repair, H-Wave® and Other Neurobiologically Based Modalities to Address Complexities of Chronic Pain in a Female Diagnosed with Reward Deficiency Syndrome (RDS): Emergence of Induction of “Dopamine Homeostasis” in the Face of the Opioid Crisis

Anish Bajaj, Kenneth Blum, Abdalla Bowirrat, Ashim Gupta, David Baron, David Fugel, Ayo Nicholson, Taylor Fitch, B. William Downs, Debasis Bagchi, Catherine A. Dennen, Rajendra D. Badgaiyan

Research output: Contribution to journalArticlepeer-review

Abstract

Addiction is a complex multifactorial condition. Established genetic factors can provide clear guidance in assessing the risk of addiction to substances and behaviors. Chronic stress can accumulate, forming difficult to recognize addiction patterns from both genetic and epigenetic (environmental) factors. Furthermore, psychological/physical/chemical stressors are typically categorized linearly, delaying identification and treatment. The patient in this case report is a Caucasian female, aged 36, who presented with chronic pain and partial disability following a surgically repaired trimalleolar fracture. The patient had a history of unresolved attention deficit disorder and an MRI scan of her brain revealed atrophy and functional asymmetry. In 2018, the patient entered the Bajaj Chiropractic Clinic, where initial treatment focused on re-establishing integrity of the spine and lower extremity biomechanics and graduated into cognitive behavior stabilization assisted by DNA pro-dopamine regulation guided by Genetic Addiction Risk Severity testing. During treatment (2018–2021), progress achieved included: improved cognitive clarity, focus, sleep, anxiety, and emotional stability in addition to pain reduction (75%); elimination of powerful analgesics; and reduced intake of previously unaddressed alcoholism. To help reduce hedonic addictive behaviors and pain, coupling of H-Wave with corrective chiropractic care seems prudent. We emphasize the importance of genetic assessment along with attempts at inducing required dopaminergic homeostasis via precision KB220PAM. It is hypothesized that from preventive care models, a new standard is emerging including self-awareness and accountability for reward deficiency as a function of hypodopaminergia. This case study documents the progression of a patient dealing with the complexities of an injury, pain management, cognitive impairment, anxiety, depression, and the application of universal health principles towards correction versus palliative care.

Original languageEnglish (US)
Article number1416
JournalJournal of Personalized Medicine
Volume12
Issue number9
DOIs
StatePublished - Sep 2022

Keywords

  • cognitive behavioral therapy
  • dopamine
  • Genetic Addiction Risk Severity (GARS)
  • H-Wave
  • KB220PAM
  • photobiomodulation
  • proprioception
  • resting state network
  • Reward Deficiency Syndrome (RDS)
  • subluxation

ASJC Scopus subject areas

  • Medicine (miscellaneous)

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