TY - JOUR
T1 - Diversity of Bipolaris species in clinical samples in the United States and their antifungal susceptibility profiles
AU - Da Cunha, K. C.
AU - Sutton, D. A.
AU - Fothergill, A. W.
AU - Cano, J.
AU - Gené, J.
AU - Madrid, H.
AU - De Hoog, S.
AU - Crous, P. W.
AU - Guarro, J.
PY - 2012/12
Y1 - 2012/12
N2 - A set of 104 isolates from human clinical samples from the United States, morphologically compatible with Bipolaris, were morphologically and molecularly identified through the sequence analysis of the internal transcribed space (ITS) region of the nuclear ribosomal DNA (rDNA). The predominant species was Bipolaris spicifera (67.3%), followed by B. hawaiiensis (18.2%), B. cynodontis (8.6%), B. micropus (2.9%), B. australiensis (2%), and B. setariae (1%). Bipolaris cynodontis, B. micropus, and B. setariae represent new records from clinical samples. The most common anatomical sites where isolates were recovered were the nasal region (30.7%), skin (19.2%), lungs (14.4%), and eyes (12.5%). The antifungal susceptibilities of 5 species of Bipolaris to 9 drugs are provided. With the exception of fluconazole and flucytosine, the antifungals tested showed good activity.
AB - A set of 104 isolates from human clinical samples from the United States, morphologically compatible with Bipolaris, were morphologically and molecularly identified through the sequence analysis of the internal transcribed space (ITS) region of the nuclear ribosomal DNA (rDNA). The predominant species was Bipolaris spicifera (67.3%), followed by B. hawaiiensis (18.2%), B. cynodontis (8.6%), B. micropus (2.9%), B. australiensis (2%), and B. setariae (1%). Bipolaris cynodontis, B. micropus, and B. setariae represent new records from clinical samples. The most common anatomical sites where isolates were recovered were the nasal region (30.7%), skin (19.2%), lungs (14.4%), and eyes (12.5%). The antifungal susceptibilities of 5 species of Bipolaris to 9 drugs are provided. With the exception of fluconazole and flucytosine, the antifungals tested showed good activity.
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U2 - 10.1128/JCM.01965-12
DO - 10.1128/JCM.01965-12
M3 - Article
C2 - 23052310
AN - SCOPUS:84869219383
SN - 0095-1137
VL - 50
SP - 4061
EP - 4066
JO - Journal of Clinical Microbiology
JF - Journal of Clinical Microbiology
IS - 12
ER -