Diurnal variation in the serotonin content and turnover in the pineal gland of the syrian hamster

Stephan Steinlechner, Richard W. Steger, Thomas S. King, Russel J. Reiter

Research output: Contribution to journalArticle

22 Scopus citations

Abstract

Serotonin and 5-hydroxyindoleacetic acid were measured in the pineal gland of Syrian hamsters by high performance liquid chromatography over a period of 24 h. A distinct 24 h rhythm was detected for both indoles. Turnover studies revealed a higher rate of serotonin synthesis during the day than during the night. We therefore suggest that the serotonin content in the pineal gland of the Syrian hamster is regulated by changes in its synthesis rate, rather than by changes of serotonin catabolism, via N-acetyltransferase activity.

Original languageEnglish (US)
Pages (from-to)167-172
Number of pages6
JournalNeuroscience Letters
Volume35
Issue number2
DOIs
StatePublished - Feb 21 1983

Keywords

  • diurnal rhythm
  • pineal gland
  • serotonin
  • turnover

ASJC Scopus subject areas

  • Neuroscience(all)

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