Diurnal variation in the serotonin content and turnover in the pineal gland of the syrian hamster

Stephan Steinlechner; Richard W. Steger; Thomas S. King; Russel J. Reiter

doi:10.1016/0304-3940(83)90545-1

Diurnal variation in the serotonin content and turnover in the pineal gland of the syrian hamster

Stephan Steinlechner, Richard W. Steger, Thomas S. King, Russel J. Reiter

Department of Cell Systems & Anatomy

Research output: Contribution to journal › Article › peer-review

22 Scopus citations

Abstract

Serotonin and 5-hydroxyindoleacetic acid were measured in the pineal gland of Syrian hamsters by high performance liquid chromatography over a period of 24 h. A distinct 24 h rhythm was detected for both indoles. Turnover studies revealed a higher rate of serotonin synthesis during the day than during the night. We therefore suggest that the serotonin content in the pineal gland of the Syrian hamster is regulated by changes in its synthesis rate, rather than by changes of serotonin catabolism, via N-acetyltransferase activity.

Original language	English (US)
Pages (from-to)	167-172
Number of pages	6
Journal	Neuroscience Letters
Volume	35
Issue number	2
DOIs	https://doi.org/10.1016/0304-3940(83)90545-1
State	Published - Feb 21 1983

Keywords

diurnal rhythm
pineal gland
serotonin
turnover

ASJC Scopus subject areas

General Neuroscience

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10.1016/0304-3940(83)90545-1

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AU - Reiter, Russel J.

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N2 - Serotonin and 5-hydroxyindoleacetic acid were measured in the pineal gland of Syrian hamsters by high performance liquid chromatography over a period of 24 h. A distinct 24 h rhythm was detected for both indoles. Turnover studies revealed a higher rate of serotonin synthesis during the day than during the night. We therefore suggest that the serotonin content in the pineal gland of the Syrian hamster is regulated by changes in its synthesis rate, rather than by changes of serotonin catabolism, via N-acetyltransferase activity.

AB - Serotonin and 5-hydroxyindoleacetic acid were measured in the pineal gland of Syrian hamsters by high performance liquid chromatography over a period of 24 h. A distinct 24 h rhythm was detected for both indoles. Turnover studies revealed a higher rate of serotonin synthesis during the day than during the night. We therefore suggest that the serotonin content in the pineal gland of the Syrian hamster is regulated by changes in its synthesis rate, rather than by changes of serotonin catabolism, via N-acetyltransferase activity.

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KW - pineal gland

KW - serotonin

KW - turnover

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Diurnal variation in the serotonin content and turnover in the pineal gland of the syrian hamster

Abstract

Keywords

ASJC Scopus subject areas

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