Diurnal rhythms of immunoreactive melatonin in the aqueous humor and serum of male pigmented rabbits

Hing Sing Yu; Richard W. Yee; Kimberly A. Howes; Russel J. Reiter

doi:10.1016/0304-3940(90)90092-N

Diurnal rhythms of immunoreactive melatonin in the aqueous humor and serum of male pigmented rabbits

Hing Sing Yu, Richard W. Yee, Kimberly A. Howes, Russel J. Reiter

Department of Cell Systems & Anatomy

Research output: Contribution to journal › Article › peer-review

42 Scopus citations

Abstract

Using specific radioimmunoassays, melatonin was quantified in the aqueous humor and serum of male pigmented rabbits adapted to 12L:12D with lights on at 06.00 h. Melatonin concentrations in the aqueous humor at 08.00 and 16.00 h were similar (mean: 5.23 pg/ml) and significantly lower than those at 22.00 and 01.00 h (mean: 22.06 pg/ml). A parallel rhythm was also demonstrated in the serum with higher melatonin concentrations (daytime mean: 75.26 pg/ml; nighttime mean: 168.94 pg/ml). We propose that the aqueous melatonin rhythm is associated with the rhythmic change in aqueous flow.

Original language	English (US)
Pages (from-to)	309-314
Number of pages	6
Journal	Neuroscience Letters
Volume	116
Issue number	3
DOIs	https://doi.org/10.1016/0304-3940(90)90092-N
State	Published - Aug 24 1990

Keywords

Aqueous humor
Diurnal
Melatonin
Rabbit
Rhythm
Serum

ASJC Scopus subject areas

General Neuroscience

Access to Document

10.1016/0304-3940(90)90092-N

Cite this

@article{974edb2e3be84cb39a0a8f0edf4f93cf,

title = "Diurnal rhythms of immunoreactive melatonin in the aqueous humor and serum of male pigmented rabbits",

abstract = "Using specific radioimmunoassays, melatonin was quantified in the aqueous humor and serum of male pigmented rabbits adapted to 12L:12D with lights on at 06.00 h. Melatonin concentrations in the aqueous humor at 08.00 and 16.00 h were similar (mean: 5.23 pg/ml) and significantly lower than those at 22.00 and 01.00 h (mean: 22.06 pg/ml). A parallel rhythm was also demonstrated in the serum with higher melatonin concentrations (daytime mean: 75.26 pg/ml; nighttime mean: 168.94 pg/ml). We propose that the aqueous melatonin rhythm is associated with the rhythmic change in aqueous flow.",

keywords = "Aqueous humor, Diurnal, Melatonin, Rabbit, Rhythm, Serum",

author = "Yu, {Hing Sing} and Yee, {Richard W.} and Howes, {Kimberly A.} and Reiter, {Russel J.}",

note = "Funding Information: The authors thank Ms. Lornell Barlow-Walden for expert technical assistance and Mrs. Linda O'Connell for excellent secretarial help. This work was partly supported by Corneal Research Funds, The University of Texas Health Science Center at San Antonio, Unrestricted Grants for Research to Prevent Blindness, Inc., and NSF Grant DCB 8711241.",

year = "1990",

month = aug,

day = "24",

doi = "10.1016/0304-3940(90)90092-N",

language = "English (US)",

volume = "116",

pages = "309--314",

journal = "Neuroscience Letters",

issn = "0304-3940",

publisher = "Elsevier Ireland Ltd",

number = "3",

}

TY - JOUR

T1 - Diurnal rhythms of immunoreactive melatonin in the aqueous humor and serum of male pigmented rabbits

AU - Yu, Hing Sing

AU - Yee, Richard W.

AU - Howes, Kimberly A.

AU - Reiter, Russel J.

N1 - Funding Information: The authors thank Ms. Lornell Barlow-Walden for expert technical assistance and Mrs. Linda O'Connell for excellent secretarial help. This work was partly supported by Corneal Research Funds, The University of Texas Health Science Center at San Antonio, Unrestricted Grants for Research to Prevent Blindness, Inc., and NSF Grant DCB 8711241.

PY - 1990/8/24

Y1 - 1990/8/24

N2 - Using specific radioimmunoassays, melatonin was quantified in the aqueous humor and serum of male pigmented rabbits adapted to 12L:12D with lights on at 06.00 h. Melatonin concentrations in the aqueous humor at 08.00 and 16.00 h were similar (mean: 5.23 pg/ml) and significantly lower than those at 22.00 and 01.00 h (mean: 22.06 pg/ml). A parallel rhythm was also demonstrated in the serum with higher melatonin concentrations (daytime mean: 75.26 pg/ml; nighttime mean: 168.94 pg/ml). We propose that the aqueous melatonin rhythm is associated with the rhythmic change in aqueous flow.

AB - Using specific radioimmunoassays, melatonin was quantified in the aqueous humor and serum of male pigmented rabbits adapted to 12L:12D with lights on at 06.00 h. Melatonin concentrations in the aqueous humor at 08.00 and 16.00 h were similar (mean: 5.23 pg/ml) and significantly lower than those at 22.00 and 01.00 h (mean: 22.06 pg/ml). A parallel rhythm was also demonstrated in the serum with higher melatonin concentrations (daytime mean: 75.26 pg/ml; nighttime mean: 168.94 pg/ml). We propose that the aqueous melatonin rhythm is associated with the rhythmic change in aqueous flow.

KW - Aqueous humor

KW - Diurnal

KW - Melatonin

KW - Rabbit

KW - Rhythm

KW - Serum

UR - http://www.scopus.com/inward/record.url?scp=0025030069&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0025030069&partnerID=8YFLogxK

U2 - 10.1016/0304-3940(90)90092-N

DO - 10.1016/0304-3940(90)90092-N

M3 - Article

C2 - 2243610

AN - SCOPUS:0025030069

SN - 0304-3940

VL - 116

SP - 309

EP - 314

JO - Neuroscience Letters

JF - Neuroscience Letters

IS - 3

ER -

Diurnal rhythms of immunoreactive melatonin in the aqueous humor and serum of male pigmented rabbits

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this