Distribution of dopamine D2 receptor mRNA splice variants in the rat by solution mhybridization/protection assay

Lenore A. Snyder, James L. Roberts, Stuart C. Sealfon

Research output: Contribution to journalArticle

38 Scopus citations

Abstract

We investigated the distribution of the two dopamine D2 receptor mRNA splice variants in the rat using a sensitive and quantitative solution hybridization/nuclease protection assay. In all brain and endocrine regions studied, both splice variants were detected and the mRNA of the longer form (D2L) was more abundant than that of the shorter form (D2S). The lowest percentages of D2S were found in the pituitary and adrenal glands.

Original languageEnglish (US)
Pages (from-to)37-40
Number of pages4
JournalNeuroscience Letters
Volume122
Issue number1
DOIs
StatePublished - Jan 14 1991
Externally publishedYes

Keywords

  • Brain
  • Pituitary
  • Polymerase chain reaction
  • Solution-hybridization
  • Subtype

ASJC Scopus subject areas

  • Neuroscience(all)

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