Disseminated zygomycosis due to Rhizopus schipperae after heatstroke

Gregory M Anstead, Deanna A. Sutton, Elizabeth H. Thompson, Irene Weitzman, Randal A Otto, Sunil K Ahuja

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

A 21-year-old woman suffered heatstroke and developed diarrhea while trekking across south Texas. The heatstroke was complicated by seizures, rhabdomyolysis, pneumonia, renal failure, and disseminated intravascular coagulation. The patient's stool and blood cultures grew Campylobacter jejuni. The patient subsequently developed paranasal and gastrointestinal zygomycosis and required surgical debridement and a prolonged course of amphotericin B. The zygomycete cultured was Rhizopus schipperae. This is only the second isolate of R. schipperae that has been described. R. schipperae is characterized by the production of clusters of up to 10 sporangiophores arising from simple but well-developed rhizoids. These asexual reproductive propagules are produced on Czapek Dox agar but are absent on routine mycology media, where only chlamydospores are observed. Despite multiorgan failure, bacteremia, and disseminated zygomycosis, the patient survived and had a good neurological outcome. Heatstroke has not been previously described as a risk factor for the development of disseminated zygomycosis.

Original languageEnglish (US)
Pages (from-to)2656-2662
Number of pages7
JournalJournal of Clinical Microbiology
Volume37
Issue number8
StatePublished - 1999

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Zygomycosis
Heat Stroke
Rhizopus
Mycology
Rhabdomyolysis
Campylobacter jejuni
Disseminated Intravascular Coagulation
Amphotericin B
Debridement
Bacteremia
Agar
Renal Insufficiency
Diarrhea
Pneumonia
Seizures

ASJC Scopus subject areas

  • Microbiology (medical)
  • Microbiology

Cite this

Anstead, G. M., Sutton, D. A., Thompson, E. H., Weitzman, I., Otto, R. A., & Ahuja, S. K. (1999). Disseminated zygomycosis due to Rhizopus schipperae after heatstroke. Journal of Clinical Microbiology, 37(8), 2656-2662.

Disseminated zygomycosis due to Rhizopus schipperae after heatstroke. / Anstead, Gregory M; Sutton, Deanna A.; Thompson, Elizabeth H.; Weitzman, Irene; Otto, Randal A; Ahuja, Sunil K.

In: Journal of Clinical Microbiology, Vol. 37, No. 8, 1999, p. 2656-2662.

Research output: Contribution to journalArticle

Anstead, GM, Sutton, DA, Thompson, EH, Weitzman, I, Otto, RA & Ahuja, SK 1999, 'Disseminated zygomycosis due to Rhizopus schipperae after heatstroke', Journal of Clinical Microbiology, vol. 37, no. 8, pp. 2656-2662.
Anstead, Gregory M ; Sutton, Deanna A. ; Thompson, Elizabeth H. ; Weitzman, Irene ; Otto, Randal A ; Ahuja, Sunil K. / Disseminated zygomycosis due to Rhizopus schipperae after heatstroke. In: Journal of Clinical Microbiology. 1999 ; Vol. 37, No. 8. pp. 2656-2662.
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