Disseminated Geosmithia argillacea infection in a German Shepherd dog

David C. Grant; Deanna A. Sutton; Christina A. Sandberg; Ronald D. Tyler; Elizabeth H. Thompson; Anna M. Romanelli; Brian L. Wickes

doi:10.1080/13693780802559023

Disseminated Geosmithia argillacea infection in a German Shepherd dog

David C. Grant, Deanna A. Sutton, Christina A. Sandberg, Ronald D. Tyler, Elizabeth H. Thompson, Anna M. Romanelli, Brian L. Wickes

Research output: Contribution to journal › Article › peer-review

36 Scopus citations

Abstract

We report a systemic mycosis in a German Shepherd dog caused by Geosmithia argillacea. Although this etiologic agent microscopically resembles a Penicillium species, and is histopathologically compatible with members of the genus Aspergillus, morphologic features and molecular characterization clearly separate it from these genera. This appears to be the first report of disseminated disease by this species in humans or animals. In vitro antifungal susceptibility testing suggests resistance to amphotericin B and voriconazole and susceptibility to caspofungin, itraconazole, and posaconazole.

Original language	English (US)
Pages (from-to)	221-226
Number of pages	6
Journal	Medical mycology
Volume	47
Issue number	2
DOIs	https://doi.org/10.1080/13693780802559023
State	Published - 2009

Keywords

Geosmithia argillacea
German Shepherd dog

ASJC Scopus subject areas

Infectious Diseases

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10.1080/13693780802559023

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title = "Disseminated Geosmithia argillacea infection in a German Shepherd dog",

abstract = "We report a systemic mycosis in a German Shepherd dog caused by Geosmithia argillacea. Although this etiologic agent microscopically resembles a Penicillium species, and is histopathologically compatible with members of the genus Aspergillus, morphologic features and molecular characterization clearly separate it from these genera. This appears to be the first report of disseminated disease by this species in humans or animals. In vitro antifungal susceptibility testing suggests resistance to amphotericin B and voriconazole and susceptibility to caspofungin, itraconazole, and posaconazole.",

keywords = "Geosmithia argillacea, German Shepherd dog",

author = "Grant, {David C.} and Sutton, {Deanna A.} and Sandberg, {Christina A.} and Tyler, {Ronald D.} and Thompson, {Elizabeth H.} and Romanelli, {Anna M.} and Wickes, {Brian L.}",

note = "Funding Information: B.L.W. is supported by grant #PR054228 from the U.S. Army Medical research and Material Command, Office of Congressionally Directed Medical Research Programs and A.M.R. Is supported by NIDCR grant # DE14318 (CO*STAR). The authors thank Dora McCarthy and Annette Fothergill for performing the antifungal susceptibility testing. The authors thank Dawn Jones and Susan King for isolation and preparation of the organism for identification and transport.",

year = "2009",

doi = "10.1080/13693780802559023",

language = "English (US)",

volume = "47",

pages = "221--226",

journal = "Medical Mycology",

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AU - Grant, David C.

AU - Sutton, Deanna A.

AU - Sandberg, Christina A.

AU - Tyler, Ronald D.

AU - Thompson, Elizabeth H.

AU - Romanelli, Anna M.

AU - Wickes, Brian L.

N1 - Funding Information: B.L.W. is supported by grant #PR054228 from the U.S. Army Medical research and Material Command, Office of Congressionally Directed Medical Research Programs and A.M.R. Is supported by NIDCR grant # DE14318 (CO*STAR). The authors thank Dora McCarthy and Annette Fothergill for performing the antifungal susceptibility testing. The authors thank Dawn Jones and Susan King for isolation and preparation of the organism for identification and transport.

PY - 2009

Y1 - 2009

N2 - We report a systemic mycosis in a German Shepherd dog caused by Geosmithia argillacea. Although this etiologic agent microscopically resembles a Penicillium species, and is histopathologically compatible with members of the genus Aspergillus, morphologic features and molecular characterization clearly separate it from these genera. This appears to be the first report of disseminated disease by this species in humans or animals. In vitro antifungal susceptibility testing suggests resistance to amphotericin B and voriconazole and susceptibility to caspofungin, itraconazole, and posaconazole.

AB - We report a systemic mycosis in a German Shepherd dog caused by Geosmithia argillacea. Although this etiologic agent microscopically resembles a Penicillium species, and is histopathologically compatible with members of the genus Aspergillus, morphologic features and molecular characterization clearly separate it from these genera. This appears to be the first report of disseminated disease by this species in humans or animals. In vitro antifungal susceptibility testing suggests resistance to amphotericin B and voriconazole and susceptibility to caspofungin, itraconazole, and posaconazole.

KW - Geosmithia argillacea

KW - German Shepherd dog

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Disseminated Geosmithia argillacea infection in a German Shepherd dog

Abstract

Keywords

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