Disposition of remoxipride in Chinese schizophrenic patients

S. K. Lin, W. H. Chang, C. P. Chien, Y. W.F. Lam, M. W. Jann

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

The disposition of remoxipride was evaluated in 13 male chronic schizophrenic patients. A single 150 mg dose of remoxipride was administered and blood sampling performed over the following 48 hours. The mean (SD) oral clearance and half-life of remoxipride were 74.46 (25.9) ml/min and 5.46 (0.87) hours, respectively. The mean (SD) AUC for remoxipride was 25,320 (9,820) ng.h/ml. A wide interpatient variability was observed. Compared to Caucasian studies there were no significant differences in the disposition of remoxipride.

Original languageEnglish (US)
Pages (from-to)17-20
Number of pages4
JournalInternational Journal of Clinical Pharmacology and Therapeutics
Volume34
Issue number1
StatePublished - Jan 23 1996

Keywords

  • Pharmacokinetics
  • Remoxipride

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)

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