Abstract
The disposition of remoxipride was evaluated in 13 male chronic schizophrenic patients. A single 150 mg dose of remoxipride was administered and blood sampling performed over the following 48 hours. The mean (SD) oral clearance and half-life of remoxipride were 74.46 (25.9) ml/min and 5.46 (0.87) hours, respectively. The mean (SD) AUC for remoxipride was 25,320 (9,820) ng.h/ml. A wide interpatient variability was observed. Compared to Caucasian studies there were no significant differences in the disposition of remoxipride.
Original language | English (US) |
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Pages (from-to) | 17-20 |
Number of pages | 4 |
Journal | International Journal of Clinical Pharmacology and Therapeutics |
Volume | 34 |
Issue number | 1 |
State | Published - 1996 |
Keywords
- Pharmacokinetics
- Remoxipride
ASJC Scopus subject areas
- General Medicine