Disparate pouch and main stomach secretions - Possible effect of antral and duodenal inhibition

Ward O. Griffen; Harlan D. Root; Earl Yonehiro; John F. Perry

doi:10.1007/BF02233880

Disparate pouch and main stomach secretions - Possible effect of antral and duodenal inhibition

Ward O. Griffen, Harlan D. Root, Earl Yonehiro, John F. Perry

Research output: Contribution to journal › Article › peer-review

Abstract

In 3 of 4 dogs, reduction by 60% of the parietal cell mass of the main stomach caused a significant increase in gastric juice output from an innervated pouch, while acid output was increased. Others' observations that vagotomy of the main stomach leads to enhanced denervated pouch secretion was confirmed. These findings are all best explained by reduction of antral and duodenal inhibition rather than vagotomy effects alone.

Original language	English (US)
Pages (from-to)	1135-1139
Number of pages	5
Journal	The American Journal of Digestive Diseases
Volume	12
Issue number	11
DOIs	https://doi.org/10.1007/BF02233880
State	Published - Nov 1 1967
Externally published	Yes

ASJC Scopus subject areas

Gastroenterology

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10.1007/BF02233880

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title = "Disparate pouch and main stomach secretions - Possible effect of antral and duodenal inhibition",

abstract = "In 3 of 4 dogs, reduction by 60% of the parietal cell mass of the main stomach caused a significant increase in gastric juice output from an innervated pouch, while acid output was increased. Others' observations that vagotomy of the main stomach leads to enhanced denervated pouch secretion was confirmed. These findings are all best explained by reduction of antral and duodenal inhibition rather than vagotomy effects alone.",

author = "Griffen, {Ward O.} and Root, {Harlan D.} and Earl Yonehiro and Perry, {John F.}",

year = "1967",

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doi = "10.1007/BF02233880",

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AU - Root, Harlan D.

AU - Yonehiro, Earl

AU - Perry, John F.

PY - 1967/11/1

Y1 - 1967/11/1

N2 - In 3 of 4 dogs, reduction by 60% of the parietal cell mass of the main stomach caused a significant increase in gastric juice output from an innervated pouch, while acid output was increased. Others' observations that vagotomy of the main stomach leads to enhanced denervated pouch secretion was confirmed. These findings are all best explained by reduction of antral and duodenal inhibition rather than vagotomy effects alone.

AB - In 3 of 4 dogs, reduction by 60% of the parietal cell mass of the main stomach caused a significant increase in gastric juice output from an innervated pouch, while acid output was increased. Others' observations that vagotomy of the main stomach leads to enhanced denervated pouch secretion was confirmed. These findings are all best explained by reduction of antral and duodenal inhibition rather than vagotomy effects alone.

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Disparate pouch and main stomach secretions - Possible effect of antral and duodenal inhibition

Abstract

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