Disparate pouch and main stomach secretions - Possible effect of antral and duodenal inhibition

Ward O. Griffen, Harlan D. Root, Earl Yonehiro, John F. Perry

Research output: Contribution to journalArticle


In 3 of 4 dogs, reduction by 60% of the parietal cell mass of the main stomach caused a significant increase in gastric juice output from an innervated pouch, while acid output was increased. Others' observations that vagotomy of the main stomach leads to enhanced denervated pouch secretion was confirmed. These findings are all best explained by reduction of antral and duodenal inhibition rather than vagotomy effects alone.

Original languageEnglish (US)
Pages (from-to)1135-1139
Number of pages5
JournalThe American Journal of Digestive Diseases
Issue number11
Publication statusPublished - Nov 1 1967


ASJC Scopus subject areas

  • Gastroenterology

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