Dismounting the MDR horse

Edward Libby, Robert Hromas

Research output: Contribution to journalComment/debatepeer-review

23 Scopus citations

Abstract

P-gp (also termed MDR1, or multidrug resistance-1) is a member of the membrane ATP cassette family that mediates efflux of several drugs commonly used to treat AML. Its expression has been correlated with an adverse outcome, 1 which was thought to occur because it mediates resistance to chemotherapy.

Original languageEnglish (US)
Pages (from-to)4037-4038
Number of pages2
JournalBlood
Volume116
Issue number20
DOIs
StatePublished - Nov 18 2010
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry
  • Immunology
  • Hematology
  • Cell Biology

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