Discovery of herpes B virus-encoded MicroRNAs

Michael I. Besecker, Mallory E. Harden, Guanglin Li, Xiu Jie Wang, Anthony Griffiths

    Research output: Contribution to journalArticle

    17 Scopus citations


    Herpes B virus (BV) naturally infects macaque monkeys and is a close relative of herpes simplex virus. BV can zoonotically infect humans to cause a rapidly ascending encephalitis with ∼80% mortality. Therefore, BV is a serious danger to those who come into contact with these monkeys or their tissues and cells. MicroRNAs are regulators of gene expression, and there have been reports of virus-encoded microRNAs. We hypothesize that BV-encoded microRNAs are important for the regulation of viral and cellular genes. Herein, we report the discovery of three herpes B virus-encoded microRNAs.

    Original languageEnglish (US)
    Pages (from-to)3413-3416
    Number of pages4
    JournalJournal of Virology
    Issue number7
    Publication statusPublished - Apr 1 2009


    ASJC Scopus subject areas

    • Microbiology
    • Immunology
    • Insect Science
    • Virology

    Cite this

    Besecker, M. I., Harden, M. E., Li, G., Wang, X. J., & Griffiths, A. (2009). Discovery of herpes B virus-encoded MicroRNAs. Journal of Virology, 83(7), 3413-3416.