TY - JOUR
T1 - Digestive Action of Human Gastric Juice
AU - Perry, John F.
AU - Yonehiro, Earl G.
AU - Ya, Po M.
AU - Root, Harlan D.
AU - Wangensteen, Owen H.
N1 - Funding Information:
Supported by: U.S.P.H.S., Graduate School, Austen S. and Anne R. Cargill, and Jay and Rose Phillips Funds for Surgical Research.
PY - 1956/6
Y1 - 1956/6
N2 - 1. The digestive capacity of human gastric juice, adjusted to pH 1.6-1.7, has been measured by perfusion of the cat's esophagus. 2. The gastric secretions of patients with duodenal ulcer, patients in the early postoperative period, and acutely ill patients showed significantly increased necrotizing effects on the esophagus as compared with controls. Gastric secretions from patients with gastric cancer and benign gastric ulcer showed no such increased digestive activity. 3. Peptic activity measured in vitro was significantly increased in duodenal ulcer patients and patients in the postoperative period. The mean pH values were significantly lower than control values in duodenal and gastric ulcer patients, postoperative patients and acutely ill patients.
AB - 1. The digestive capacity of human gastric juice, adjusted to pH 1.6-1.7, has been measured by perfusion of the cat's esophagus. 2. The gastric secretions of patients with duodenal ulcer, patients in the early postoperative period, and acutely ill patients showed significantly increased necrotizing effects on the esophagus as compared with controls. Gastric secretions from patients with gastric cancer and benign gastric ulcer showed no such increased digestive activity. 3. Peptic activity measured in vitro was significantly increased in duodenal ulcer patients and patients in the postoperative period. The mean pH values were significantly lower than control values in duodenal and gastric ulcer patients, postoperative patients and acutely ill patients.
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U2 - 10.3181/00379727-92-22439
DO - 10.3181/00379727-92-22439
M3 - Article
C2 - 13350309
AN - SCOPUS:0342969404
VL - 92
SP - 237
EP - 240
JO - Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N. Y.)
JF - Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N. Y.)
SN - 1535-3702
IS - 2
ER -