Diffuse T-cell lymphoma preceded by nodular lymphoma

J. C. Jennette, R. L. Reddick, A. W. Saunders, A. S. Wilkman

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13 Scopus citations


A patient with a nodular lymphoma morphologically indistinguishable from follicular B-cell lymphoma subsequently developed a diffuse T-cell lymphoma. This T-cell lymphoma displayed characteristics analogous to mature T-lymphocytes, and typed as a suppressor/cytotoxic T-cell with monoclonal antibodies. The light and electron microscopic morphology of the T-cell lymphoma was similar to that reported for node-based T- cell lymphomas. There was a polymorphous proliferation of variably transformed lymphocytes including immunoblasts. This case could represent either a nodular form of T-cell lymphoma converting to a diffuse T-cell lymphoma, or a follicular B-cell lymphoma preceding, and possibly inducing, a suppressor T-cell lymphoma.

Original languageEnglish (US)
Pages (from-to)242-248
Number of pages7
JournalAmerican journal of clinical pathology
Issue number2
StatePublished - 1982
Externally publishedYes

ASJC Scopus subject areas

  • Pathology and Forensic Medicine


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