Differential susceptibility of mono- and di-O-alkyl ether phosphoglycerides to acetolysis.

R. Kumar, Susan E Weintraub, D. J. Hanahan

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

The effectiveness of acetolysis as a tool in structural characterization of mono- and di-O-alkyl phosphoglycerides was investigated. Surprisingly, it was found that the di-O-alkyl phosphoglycerides were resistant to attack during acetolysis, whereas the mono-ether types, with a free hydroxyl function or an ester on carbon-2, were easily attacked at the glycerol-phosphate bond. On the other hand, Vitride reduction occurred readily with the mono-ether or di-ether phosphoglycerides. The implications of these findings as they relate to identification of ether phospholipids in tissues are discussed.

Original languageEnglish (US)
Pages (from-to)930-937
Number of pages8
JournalJournal of Lipid Research
Volume24
Issue number7
StatePublished - Jul 1983
Externally publishedYes

Fingerprint

Glycerophospholipids
Ether
Phospholipid Ethers
Hydroxyl Radical
Glycerol
Esters
Carbon
Phosphates
Tissue

ASJC Scopus subject areas

  • Endocrinology

Cite this

Differential susceptibility of mono- and di-O-alkyl ether phosphoglycerides to acetolysis. / Kumar, R.; Weintraub, Susan E; Hanahan, D. J.

In: Journal of Lipid Research, Vol. 24, No. 7, 07.1983, p. 930-937.

Research output: Contribution to journalArticle

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