Abstract
The reinforcing effects of diazepam were examined in 4 female patients with generalized anxiety disorder but without histories of drug abuse. Under double-blind conditions, patients were given medication capsules containing either 4 mg diazepam or placebo that they could use 'as needed' for anxiety. After a 1-week sampling period for each medication, participants repeatedly chose which medication they preferred over the next 4 weeks. Reinforcing effects of diazepam were demonstrated in 3 participants who showed exclusive diazepam preference. The results suggest procedures whereby drug self-medication behavior may be studied in an outpatient environment.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 308-314 |
| Number of pages | 7 |
| Journal | Experimental and Clinical Psychopharmacology |
| Volume | 4 |
| Issue number | 3 |
| DOIs | |
| State | Published - Jan 1 1996 |
ASJC Scopus subject areas
- Pharmacology
- Psychiatry and Mental health
- Pharmacology (medical)
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Roache, J. D., Stanley, M. A., Creson, D. L., Meisch, R. A., & Shah, N. N. (1996). Diazepam reinforcement in anxious patients. Experimental and Clinical Psychopharmacology, 4(3), 308-314. https://doi.org/10.1037/1064-1297.4.3.308