Diagnosis and treatment of adults with community-acquired pneumonia

Joshua P. Metlay; Grant W. Waterer; Ann C. Long; Antonio Anzueto; Jan Brozek; Kristina Crothers; Laura A. Cooley; Nathan C. Dean; Michael J. Fine; Scott A. Flanders; Marie R. Griffin; Mark L. Metersky; Daniel M. Musher; Marcos I. Restrepo; Cynthia G. Whitney

doi:10.1164/rccm.201908-1581ST

Diagnosis and treatment of adults with community-acquired pneumonia

Joshua P. Metlay, Grant W. Waterer, Ann C. Long, Antonio Anzueto, Jan Brozek, Kristina Crothers, Laura A. Cooley, Nathan C. Dean, Michael J. Fine, Scott A. Flanders, Marie R. Griffin, Mark L. Metersky, Daniel M. Musher, Marcos I. Restrepo, Cynthia G. Whitney

Research output: Contribution to journal › Article › peer-review

2182 Scopus citations

Abstract

Background: This document provides evidence-based clinical practice guidelines on the management of adult patients with community-acquired pneumonia. Methods: A multidisciplinary panel conducted pragmatic systematic reviews of the relevant research and applied Grading of Recommendations, Assessment, Development, and Evaluation methodology for clinical recommendations. Results: The panel addressed 16 specific areas for recommendations spanning questions of diagnostic testing, determination of site of care, selection of initial empiric antibiotic therapy, and subsequent management decisions. Although some recommendations remain unchanged from the 2007 guideline, the availability of results from new therapeutic trials and epidemiological investigations led to revised recommendations for empiric treatment strategies and additional management decisions. Conclusions: The panel formulated and provided the rationale for recommendations on selected diagnostic and treatment strategies for adult patients with community-acquired pneumonia.

Original language	English (US)
Pages (from-to)	E45-E67
Journal	American Journal of Respiratory and Critical Care Medicine
Volume	200
Issue number	7
DOIs	https://doi.org/10.1164/rccm.201908-1581ST
State	Published - Oct 1 2019

Keywords

Community-acquired pneumonia
Patient management
Pneumonia

ASJC Scopus subject areas

Pulmonary and Respiratory Medicine
Critical Care and Intensive Care Medicine

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10.1164/rccm.201908-1581ST

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Metlay, J. P., Waterer, G. W., Long, A. C., Anzueto, A., Brozek, J., Crothers, K., Cooley, L. A., Dean, N. C., Fine, M. J., Flanders, S. A., Griffin, M. R., Metersky, M. L., Musher, D. M., Restrepo, M. I., & Whitney, C. G. (2019). Diagnosis and treatment of adults with community-acquired pneumonia. American Journal of Respiratory and Critical Care Medicine, 200(7), E45-E67. https://doi.org/10.1164/rccm.201908-1581ST

Metlay, JP, Waterer, GW, Long, AC, Anzueto, A, Brozek, J, Crothers, K, Cooley, LA, Dean, NC, Fine, MJ, Flanders, SA, Griffin, MR, Metersky, ML, Musher, DM, Restrepo, MI & Whitney, CG 2019, 'Diagnosis and treatment of adults with community-acquired pneumonia', American Journal of Respiratory and Critical Care Medicine, vol. 200, no. 7, pp. E45-E67. https://doi.org/10.1164/rccm.201908-1581ST

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title = "Diagnosis and treatment of adults with community-acquired pneumonia",

abstract = "Background: This document provides evidence-based clinical practice guidelines on the management of adult patients with community-acquired pneumonia. Methods: A multidisciplinary panel conducted pragmatic systematic reviews of the relevant research and applied Grading of Recommendations, Assessment, Development, and Evaluation methodology for clinical recommendations. Results: The panel addressed 16 specific areas for recommendations spanning questions of diagnostic testing, determination of site of care, selection of initial empiric antibiotic therapy, and subsequent management decisions. Although some recommendations remain unchanged from the 2007 guideline, the availability of results from new therapeutic trials and epidemiological investigations led to revised recommendations for empiric treatment strategies and additional management decisions. Conclusions: The panel formulated and provided the rationale for recommendations on selected diagnostic and treatment strategies for adult patients with community-acquired pneumonia.",

keywords = "Community-acquired pneumonia, Patient management, Pneumonia",

author = "Metlay, {Joshua P.} and Waterer, {Grant W.} and Long, {Ann C.} and Antonio Anzueto and Jan Brozek and Kristina Crothers and Cooley, {Laura A.} and Dean, {Nathan C.} and Fine, {Michael J.} and Flanders, {Scott A.} and Griffin, {Marie R.} and Metersky, {Mark L.} and Musher, {Daniel M.} and Restrepo, {Marcos I.} and Whitney, {Cynthia G.}",

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doi = "10.1164/rccm.201908-1581ST",

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AU - Waterer, Grant W.

AU - Long, Ann C.

AU - Anzueto, Antonio

AU - Brozek, Jan

AU - Crothers, Kristina

AU - Cooley, Laura A.

AU - Dean, Nathan C.

AU - Fine, Michael J.

AU - Flanders, Scott A.

AU - Griffin, Marie R.

AU - Metersky, Mark L.

AU - Musher, Daniel M.

AU - Restrepo, Marcos I.

AU - Whitney, Cynthia G.

PY - 2019/10/1

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N2 - Background: This document provides evidence-based clinical practice guidelines on the management of adult patients with community-acquired pneumonia. Methods: A multidisciplinary panel conducted pragmatic systematic reviews of the relevant research and applied Grading of Recommendations, Assessment, Development, and Evaluation methodology for clinical recommendations. Results: The panel addressed 16 specific areas for recommendations spanning questions of diagnostic testing, determination of site of care, selection of initial empiric antibiotic therapy, and subsequent management decisions. Although some recommendations remain unchanged from the 2007 guideline, the availability of results from new therapeutic trials and epidemiological investigations led to revised recommendations for empiric treatment strategies and additional management decisions. Conclusions: The panel formulated and provided the rationale for recommendations on selected diagnostic and treatment strategies for adult patients with community-acquired pneumonia.

AB - Background: This document provides evidence-based clinical practice guidelines on the management of adult patients with community-acquired pneumonia. Methods: A multidisciplinary panel conducted pragmatic systematic reviews of the relevant research and applied Grading of Recommendations, Assessment, Development, and Evaluation methodology for clinical recommendations. Results: The panel addressed 16 specific areas for recommendations spanning questions of diagnostic testing, determination of site of care, selection of initial empiric antibiotic therapy, and subsequent management decisions. Although some recommendations remain unchanged from the 2007 guideline, the availability of results from new therapeutic trials and epidemiological investigations led to revised recommendations for empiric treatment strategies and additional management decisions. Conclusions: The panel formulated and provided the rationale for recommendations on selected diagnostic and treatment strategies for adult patients with community-acquired pneumonia.

KW - Community-acquired pneumonia

KW - Patient management

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Diagnosis and treatment of adults with community-acquired pneumonia

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