Diagnosis and management of bleeding disorder in a child

Amit Sarnaik, Deepak Kamat, Nirupama Kannikeswaran

Research output: Contribution to journalReview articlepeer-review

9 Scopus citations


Children with symptoms of bleeding and bruising are commonly seen in clinical practice. Primary care providers should be able to decide when and whether evaluation for bleeding disorder is warranted. This decision depends on oneg's index of suspicion for bleeding disorder based on history, physical examination, and screening laboratory investigations. Knowledge of the hemostatic physiology is essential to be able to order appropriate laboratory investigations and their accurate interpretation. Prothrombin time (PT), activated partial thromboplastin time (aPTT), and blood platelet concentration constitute the initial diagnostic work up of any bleeding disorder. Abnormality in any of these parameters in a child with excessive bleeding should lead to presumptive diagnosis of bleeding disorder and trigger referral to a hematologist for confirmation and definitive treatment. Awareness of basic treatment principles for management of bleeding/clotting disorders may prepare the provider to develop appropriate management plans, especially in a life threatening situation.

Original languageEnglish (US)
Pages (from-to)422-431
Number of pages10
JournalClinical Pediatrics
Issue number5
StatePublished - May 1 2010
Externally publishedYes


  • Bleeding disorder
  • Children
  • Diagnosis
  • Hemostasis
  • Treatment

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health


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