Development of composite symptom variables for quantitative analysis of genitourinary symptomatology in women

Jeanna M. Piper, Jeffrey E. Korte, Alan E C Holden, Rochelle N. Shain, Sondra Perdue, Jane D. Champion, Edward R. Newton

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Gonorrhoea and chlamydia infections in women are often regarded as asymptomatic. Syndromic management of sexually transmitted disease (STDs), however, is partially based on vaginal symptoms. We sought to better identify STD-associated symptoms in women by development of composite genitourinary symptom constructs. Standard symptoms were stratified, based on their descriptors (amount, frequency, severity, etc.), into pathological (likely to be STD-associated) and intermediate (unlikely to be STD-related). Simple symptoms and composite symptom constructs were significantly more common in women with STD infections (chlamydia, gonorrhoea and/or trichomonas) than those without infection (six months later). Logistic regression confirmed the association of each pathological symptom construct individually with gonorrhoea, chlamydia and trichomonas. Composite symptom constructs improve the specificity for detecting STD infections in women.

Original languageEnglish (US)
Pages (from-to)128-132
Number of pages5
JournalInternational Journal of STD and AIDS
Volume16
Issue number2
DOIs
StatePublished - Feb 2005

Fingerprint

Sexually Transmitted Diseases
Gonorrhea
Trichomonas
Chlamydia
Chlamydia Infections
Logistic Models
Infection

Keywords

  • Chlamydia
  • Genitourinary symptoms
  • Gonorrhoea
  • Sexually transmitted diseases

ASJC Scopus subject areas

  • Dermatology
  • Public Health, Environmental and Occupational Health
  • Microbiology (medical)
  • Immunology

Cite this

Piper, J. M., Korte, J. E., Holden, A. E. C., Shain, R. N., Perdue, S., Champion, J. D., & Newton, E. R. (2005). Development of composite symptom variables for quantitative analysis of genitourinary symptomatology in women. International Journal of STD and AIDS, 16(2), 128-132. https://doi.org/10.1258/0956462053057549

Development of composite symptom variables for quantitative analysis of genitourinary symptomatology in women. / Piper, Jeanna M.; Korte, Jeffrey E.; Holden, Alan E C; Shain, Rochelle N.; Perdue, Sondra; Champion, Jane D.; Newton, Edward R.

In: International Journal of STD and AIDS, Vol. 16, No. 2, 02.2005, p. 128-132.

Research output: Contribution to journalArticle

Piper, JM, Korte, JE, Holden, AEC, Shain, RN, Perdue, S, Champion, JD & Newton, ER 2005, 'Development of composite symptom variables for quantitative analysis of genitourinary symptomatology in women', International Journal of STD and AIDS, vol. 16, no. 2, pp. 128-132. https://doi.org/10.1258/0956462053057549
Piper, Jeanna M. ; Korte, Jeffrey E. ; Holden, Alan E C ; Shain, Rochelle N. ; Perdue, Sondra ; Champion, Jane D. ; Newton, Edward R. / Development of composite symptom variables for quantitative analysis of genitourinary symptomatology in women. In: International Journal of STD and AIDS. 2005 ; Vol. 16, No. 2. pp. 128-132.
@article{86d34f5ec0c84e69a163e2f76544ada2,
title = "Development of composite symptom variables for quantitative analysis of genitourinary symptomatology in women",
abstract = "Gonorrhoea and chlamydia infections in women are often regarded as asymptomatic. Syndromic management of sexually transmitted disease (STDs), however, is partially based on vaginal symptoms. We sought to better identify STD-associated symptoms in women by development of composite genitourinary symptom constructs. Standard symptoms were stratified, based on their descriptors (amount, frequency, severity, etc.), into pathological (likely to be STD-associated) and intermediate (unlikely to be STD-related). Simple symptoms and composite symptom constructs were significantly more common in women with STD infections (chlamydia, gonorrhoea and/or trichomonas) than those without infection (six months later). Logistic regression confirmed the association of each pathological symptom construct individually with gonorrhoea, chlamydia and trichomonas. Composite symptom constructs improve the specificity for detecting STD infections in women.",
keywords = "Chlamydia, Genitourinary symptoms, Gonorrhoea, Sexually transmitted diseases",
author = "Piper, {Jeanna M.} and Korte, {Jeffrey E.} and Holden, {Alan E C} and Shain, {Rochelle N.} and Sondra Perdue and Champion, {Jane D.} and Newton, {Edward R.}",
year = "2005",
month = "2",
doi = "10.1258/0956462053057549",
language = "English (US)",
volume = "16",
pages = "128--132",
journal = "International Journal of STD and AIDS",
issn = "0956-4624",
publisher = "SAGE Publications Ltd",
number = "2",

}

TY - JOUR

T1 - Development of composite symptom variables for quantitative analysis of genitourinary symptomatology in women

AU - Piper, Jeanna M.

AU - Korte, Jeffrey E.

AU - Holden, Alan E C

AU - Shain, Rochelle N.

AU - Perdue, Sondra

AU - Champion, Jane D.

AU - Newton, Edward R.

PY - 2005/2

Y1 - 2005/2

N2 - Gonorrhoea and chlamydia infections in women are often regarded as asymptomatic. Syndromic management of sexually transmitted disease (STDs), however, is partially based on vaginal symptoms. We sought to better identify STD-associated symptoms in women by development of composite genitourinary symptom constructs. Standard symptoms were stratified, based on their descriptors (amount, frequency, severity, etc.), into pathological (likely to be STD-associated) and intermediate (unlikely to be STD-related). Simple symptoms and composite symptom constructs were significantly more common in women with STD infections (chlamydia, gonorrhoea and/or trichomonas) than those without infection (six months later). Logistic regression confirmed the association of each pathological symptom construct individually with gonorrhoea, chlamydia and trichomonas. Composite symptom constructs improve the specificity for detecting STD infections in women.

AB - Gonorrhoea and chlamydia infections in women are often regarded as asymptomatic. Syndromic management of sexually transmitted disease (STDs), however, is partially based on vaginal symptoms. We sought to better identify STD-associated symptoms in women by development of composite genitourinary symptom constructs. Standard symptoms were stratified, based on their descriptors (amount, frequency, severity, etc.), into pathological (likely to be STD-associated) and intermediate (unlikely to be STD-related). Simple symptoms and composite symptom constructs were significantly more common in women with STD infections (chlamydia, gonorrhoea and/or trichomonas) than those without infection (six months later). Logistic regression confirmed the association of each pathological symptom construct individually with gonorrhoea, chlamydia and trichomonas. Composite symptom constructs improve the specificity for detecting STD infections in women.

KW - Chlamydia

KW - Genitourinary symptoms

KW - Gonorrhoea

KW - Sexually transmitted diseases

UR - http://www.scopus.com/inward/record.url?scp=14644391528&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=14644391528&partnerID=8YFLogxK

U2 - 10.1258/0956462053057549

DO - 10.1258/0956462053057549

M3 - Article

C2 - 15807940

AN - SCOPUS:14644391528

VL - 16

SP - 128

EP - 132

JO - International Journal of STD and AIDS

JF - International Journal of STD and AIDS

SN - 0956-4624

IS - 2

ER -