Development of a Patient-Centered Software System to Facilitate Effective Management of Bipolar Disorder

  • Charles L. Bowden
  • , Richard Priesmeyer
  • , Mauricio Tohen
  • , Vivek Singh
  • , Joseph R. Calabrese
  • , Terry Ketter
  • , Andrew Nierenberg
  • , Michael E. Thase
  • , Gregg Siegel
  • , Leslie H. Siegel
  • , Jim Mintz
  • , Rif S. El-Mallakh
  • , Susan L. McElroy
  • , Melissa Martinez

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

Objective: Self-management of bipolar disorder (BD) is an important component of treatment. Methods: We developed a patient-centered computational software system based on concepts from nonlinear systems (chaos) theory with mobile access to assist in managing BD known as KIOS. KIOS tracks interacting symptoms to determine theprecise state of a BD patient. Once the patient’s state is identified and the trajectory of the patient established, specific advice is generated to help manage the course of the disease. KIOS also provides analytics that can be used by clinicians and researchers to track outcomes and the course of illness. A 12-week field test was completed. Results: In 20 BD subjects, use of KIOS was associated with improvements in primary symptom categories of BD. Usability and generated advice were rated as a median of 6 out of a maximum of 7.

Original languageEnglish (US)
Pages (from-to)8-19
Number of pages12
JournalPsychopharmacology bulletin
Volume51
Issue number2
StatePublished - 2021
Externally publishedYes

Keywords

  • bipolar
  • chronic disease
  • patient guidance
  • self-assessment
  • smart phone
  • treatment

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Pharmacology (medical)

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