Development of a dimethylarginine dimethylaminohydrolase (DDAH) assay for high-throughput chemical screening

Pharmacology, Toxicology and Pharmaceutical Science

• Dimethylargininase 100%
• Nitric Oxide 71%
• 6 N,n' Dimethylarginine 42%
• N(g),n(g) Dimethylarginine 42%
• Nitric Oxide Synthase 28%
• Atherosclerosis 14%
• Malignant Neoplasm 14%
• Inducible Nitric Oxide Synthase 14%
• Fibrosing Alveolitis 14%
• Insulin Resistance 14%
• Sepsis 14%
• Vascular Disease 14%
• Migraine 14%
• Hypertension 14%

Biochemistry, Genetics and Molecular Biology

• Chemical Screening 100%
• Dimethylargininase 100%
• Nitric Oxide 71%
• Small Molecule 42%
• Nitric Oxide Synthase 42%
• Oxidative Stress 14%
• Homeostasis 14%
• Insulin Resistance 14%

Chemistry

• Dimethylarginine 100%
• Nitric Oxide 50%
• Nitric Oxide Synthase 30%
• Metabolic 20%
• Insulin Derivative 10%
• Signalling Molecule 10%
• Oxidative Stress 10%