Development and validation of a high-performance liquid chromatography assay for voriconazole

Gennethel J. Pennick; Martin Clark; Deanna A. Sutton; Michael G. Rinaldi

doi:10.1128/AAC.47.7.2348-2350.2003

Development and validation of a high-performance liquid chromatography assay for voriconazole

Gennethel J. Pennick, Martin Clark, Deanna A. Sutton, Michael G. Rinaldi

Department of Pathology

Research output: Contribution to journal › Article › peer-review

123 Scopus citations

Abstract

An analytical method for the determination of voriconazole (UK-109,496; Pfizer) in plasma was developed and validated. The method utilizes solid-phase extraction technology and high-performance liquid chromatography. The lower limit of quantitation is 0.2 μg/ml, and the range of linearity tested was 0.2 to 10 μg/ml.

Original language	English (US)
Pages (from-to)	2348-2350
Number of pages	3
Journal	Antimicrobial agents and chemotherapy
Volume	47
Issue number	7
DOIs	https://doi.org/10.1128/AAC.47.7.2348-2350.2003
State	Published - Jul 1 2003

ASJC Scopus subject areas

Pharmacology (medical)
Infectious Diseases
Pharmacology

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abstract = "An analytical method for the determination of voriconazole (UK-109,496; Pfizer) in plasma was developed and validated. The method utilizes solid-phase extraction technology and high-performance liquid chromatography. The lower limit of quantitation is 0.2 μg/ml, and the range of linearity tested was 0.2 to 10 μg/ml.",

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Development and validation of a high-performance liquid chromatography assay for voriconazole

Abstract

ASJC Scopus subject areas

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