Determination of dexamethasone dose for cortisol suppression in adult common marmosets (Callithrix jacchus)

Kimberley A. Phillips; Matthew Lopez; Adam B. Salmon; Corinna N. Ross; David H. Abbott; John P. Capitanio

doi:10.1111/jmp.12602

Determination of dexamethasone dose for cortisol suppression in adult common marmosets (Callithrix jacchus)

Kimberley A. Phillips
, Matthew Lopez
, Adam B. Salmon
, Corinna N. Ross
, David H. Abbott
, John P. Capitanio

Research output: Contribution to journal › Article › peer-review

Abstract

We conducted a dose–response study of dexamethasone to investigate an optimal dexamethasone suppression test for common marmosets. Twelve marmosets received 0.1, 0.5, or 1.0 mg/kg dexamethasone. Doses of 0.5 and 1.0 mg/kg both suppressed endogenous cortisol for at least 18 h with greater individual variability in the lower 0.5 mg/kg dose.

Original language	English (US)
Pages (from-to)	407-410
Number of pages	4
Journal	Journal of medical primatology
Volume	51
Issue number	6
DOIs	https://doi.org/10.1111/jmp.12602
State	Published - Dec 2022
Externally published	Yes

Keywords

common marmoset
dexamethasone suppression test
glucocorticoid

ASJC Scopus subject areas

Animal Science and Zoology
General Veterinary

Access to Document

10.1111/jmp.12602

Cite this

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abstract = "We conducted a dose–response study of dexamethasone to investigate an optimal dexamethasone suppression test for common marmosets. Twelve marmosets received 0.1, 0.5, or 1.0 mg/kg dexamethasone. Doses of 0.5 and 1.0 mg/kg both suppressed endogenous cortisol for at least 18 h with greater individual variability in the lower 0.5 mg/kg dose.",

keywords = "common marmoset, dexamethasone suppression test, glucocorticoid",

author = "Phillips, \{Kimberley A.\} and Matthew Lopez and Salmon, \{Adam B.\} and Ross, \{Corinna N.\} and Abbott, \{David H.\} and Capitanio, \{John P.\}",

note = "Publisher Copyright: {\textcopyright} 2022 The Authors. Journal of Medical Primatology published by John Wiley \& Sons Ltd.",

year = "2022",

month = dec,

doi = "10.1111/jmp.12602",

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AU - Phillips, Kimberley A.

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AU - Salmon, Adam B.

AU - Ross, Corinna N.

AU - Abbott, David H.

AU - Capitanio, John P.

PY - 2022/12

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N2 - We conducted a dose–response study of dexamethasone to investigate an optimal dexamethasone suppression test for common marmosets. Twelve marmosets received 0.1, 0.5, or 1.0 mg/kg dexamethasone. Doses of 0.5 and 1.0 mg/kg both suppressed endogenous cortisol for at least 18 h with greater individual variability in the lower 0.5 mg/kg dose.

AB - We conducted a dose–response study of dexamethasone to investigate an optimal dexamethasone suppression test for common marmosets. Twelve marmosets received 0.1, 0.5, or 1.0 mg/kg dexamethasone. Doses of 0.5 and 1.0 mg/kg both suppressed endogenous cortisol for at least 18 h with greater individual variability in the lower 0.5 mg/kg dose.

KW - common marmoset

KW - dexamethasone suppression test

KW - glucocorticoid

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UR - https://www.scopus.com/pages/publications/85133474868#tab=citedBy

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ER -

Determination of dexamethasone dose for cortisol suppression in adult common marmosets (Callithrix jacchus)

Abstract

Keywords

ASJC Scopus subject areas

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