Determination of dexamethasone dose for cortisol suppression in adult common marmosets (Callithrix jacchus)

Kimberley A. Phillips, Matthew Lopez, Adam B. Salmon, Corinna N. Ross, David H. Abbott, John P. Capitanio

Research output: Contribution to journalArticlepeer-review

Abstract

We conducted a dose–response study of dexamethasone to investigate an optimal dexamethasone suppression test for common marmosets. Twelve marmosets received 0.1, 0.5, or 1.0 mg/kg dexamethasone. Doses of 0.5 and 1.0 mg/kg both suppressed endogenous cortisol for at least 18 h with greater individual variability in the lower 0.5 mg/kg dose.

Original languageEnglish (US)
Pages (from-to)407-410
Number of pages4
JournalJournal of medical primatology
Volume51
Issue number6
DOIs
StatePublished - Dec 2022
Externally publishedYes

Keywords

  • common marmoset
  • dexamethasone suppression test
  • glucocorticoid

ASJC Scopus subject areas

  • Animal Science and Zoology
  • veterinary(all)

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