Determination of dexamethasone dose for cortisol suppression in adult common marmosets (Callithrix jacchus)

Kimberley A. Phillips; Matthew Lopez; Adam B. Salmon; Corinna N. Ross; David H. Abbott; John P. Capitanio

doi:10.1111/jmp.12602

Determination of dexamethasone dose for cortisol suppression in adult common marmosets (Callithrix jacchus)

Kimberley A. Phillips, Matthew Lopez, Adam B. Salmon, Corinna N. Ross, David H. Abbott, John P. Capitanio

Research output: Contribution to journal › Article › peer-review

Abstract

We conducted a dose–response study of dexamethasone to investigate an optimal dexamethasone suppression test for common marmosets. Twelve marmosets received 0.1, 0.5, or 1.0 mg/kg dexamethasone. Doses of 0.5 and 1.0 mg/kg both suppressed endogenous cortisol for at least 18 h with greater individual variability in the lower 0.5 mg/kg dose.

Original language	English (US)
Pages (from-to)	407-410
Number of pages	4
Journal	Journal of medical primatology
Volume	51
Issue number	6
DOIs	https://doi.org/10.1111/jmp.12602
State	Published - Dec 2022
Externally published	Yes

Keywords

common marmoset
dexamethasone suppression test
glucocorticoid

ASJC Scopus subject areas

Animal Science and Zoology
General Veterinary

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10.1111/jmp.12602

Cite this

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abstract = "We conducted a dose–response study of dexamethasone to investigate an optimal dexamethasone suppression test for common marmosets. Twelve marmosets received 0.1, 0.5, or 1.0 mg/kg dexamethasone. Doses of 0.5 and 1.0 mg/kg both suppressed endogenous cortisol for at least 18 h with greater individual variability in the lower 0.5 mg/kg dose.",

keywords = "common marmoset, dexamethasone suppression test, glucocorticoid",

author = "Phillips, {Kimberley A.} and Matthew Lopez and Salmon, {Adam B.} and Ross, {Corinna N.} and Abbott, {David H.} and Capitanio, {John P.}",

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AU - Abbott, David H.

AU - Capitanio, John P.

PY - 2022/12

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AB - We conducted a dose–response study of dexamethasone to investigate an optimal dexamethasone suppression test for common marmosets. Twelve marmosets received 0.1, 0.5, or 1.0 mg/kg dexamethasone. Doses of 0.5 and 1.0 mg/kg both suppressed endogenous cortisol for at least 18 h with greater individual variability in the lower 0.5 mg/kg dose.

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Determination of dexamethasone dose for cortisol suppression in adult common marmosets (Callithrix jacchus)

Abstract

Keywords

ASJC Scopus subject areas

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