Detection of Minute Gastrointestinal Bleeding Utilizing Radioactive Iron, Fe59

Earl G. Yonehiro, Harlan D. Root, John F. Perry, James F. Marvin, Owen H. Wangensteen

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

1. Excretion patterns of intravenously administered radioactive iron in the stool of normal dogs and in dogs with histamine induced bleeding of the gastrointestinal tract have been compared. 2. Levels of stool radioactivity have been measured following intragastric administration of known amounts of isotope-labelled blood. 3. Radioactivity in the stool can be utilized for detection of occult bleeding. 4. Comparative evaluation following administration of known small quantities of isotope-labelled blood (Fe59) indicates definitely that this test is considerably more sensitive than the guaiac test.

Original languageEnglish (US)
Pages (from-to)339-341
Number of pages3
JournalProceedings of the Society for Experimental Biology and Medicine
Volume98
Issue number2
DOIs
StatePublished - Jun 1958
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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