Abstract
Fluorescence imaging using hematoporphyrin derivative (HpD) or Photofrin II as a tumor marker has been used for localization of early bronchogenic carcinoma. Wider clinical application of HpD or Photofrin II as a cancer imaging agent has been hampered by the potentially serious and prolonged skin photosensitivity. Using a sensitive fluorescence bronchoscope system with a ratio fluorometer probe, carcinoma in situ was detected in four patients with low dose Photofrin II (0.25 mg/kg) with no apparent skin phototoxicity to 30 J/cm2 visible light on skin photosensitivity test.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 333-337 |
| Number of pages | 5 |
| Journal | Chest |
| Volume | 97 |
| Issue number | 2 |
| DOIs | |
| State | Published - Jan 1 1990 |
ASJC Scopus subject areas
- Pulmonary and Respiratory Medicine
- Critical Care and Intensive Care Medicine
- Cardiology and Cardiovascular Medicine
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Lam, S., Palcic, B., McLean, D., Hung, J., Korbelik, M., & Profio, A. E. (1990). Detection of early lung cancer using low dose Photofrin II. Chest, 97(2), 333-337. https://doi.org/10.1378/chest.97.2.333