Abstract
Spleen cells and peripheral blood lymphocytes from chickens infected with reticuloendotheliosis virus (REV) were depressed in their responsiveness to phytohemagglutinin (PHA). When spleen cells from uninfected chickens were co-cultured with spleen cells from chickens infected with REV at 2 weeks of age, the PHA response by the normal cells was completely suppressed. Although spleen cells from chickens infected with REV at 6 or 9 weeks of age were also suppressed in their ability to respond to PHA, they did not suppress the mitogenic response of normal cells in mixed cultures.
Original language | English (US) |
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Pages (from-to) | 1321-1325 |
Number of pages | 5 |
Journal | Journal of Immunology |
Volume | 120 |
Issue number | 4 |
State | Published - Dec 1 1978 |
ASJC Scopus subject areas
- Immunology and Allergy
- Immunology